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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+23.77%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$4.34B
AUM Growth
+$467M
Cap. Flow
-$99.7M
Cap. Flow %
-2.3%
Top 10 Hldgs %
48.91%
Holding
111
New
4
Increased
17
Reduced
21
Closed
25

Top Buys

Rank Stock Value
1
RARE icon
Ultragenyx Pharmaceutical
RARE
+$50.7M
2
ISEE
IVERIC bio, Inc. Common Stock
ISEE
+$47.6M
3
PTCT icon
PTC Therapeutics
PTCT
+$28.2M
4
IMCR icon
Immunocore
IMCR
+$21.7M
5
AXSM icon
Axsome Therapeutics
AXSM
+$13.2M

Top Sells

Rank Stock Value
1
TNDM icon
Tandem Diabetes Care
TNDM
+$32.9M
2
QTRX icon
Quanterix
QTRX
+$29.5M
3
VERU icon
Veru
VERU
+$25.1M
4
GMED icon
Globus Medical
GMED
+$22.5M
5
AXNX
Axonics, Inc. Common Stock
AXNX
+$20.3M

Sector Composition

Rank Sector Weight
1 Healthcare 99.21%
2 Financials 0.67%
3 Industrials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
OYST
51
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
$11.5M 0.26%
2,044,312
-14,192
-0.7% -$88.9K
WHWK
52
Whitehawk Therapeutics
WHWK
$271M
$10.8M 0.25%
764,701
– –
ALLK
53
DELISTED
Allakos
ALLK
$10.1M 0.23%
+1,643,500
New +$6.88M
GLUE icon
54
Monte Rosa Therapeutics
GLUE
$1.35B
$9.92M 0.23%
1,214,572
– –
OBIO icon
55
Orchestra BioMed
OBIO
$254M
$9.9M 0.23%
+1,000,000
New +$9.91M
IMUX icon
56
Immunic
IMUX
$195M
$8.73M 0.2%
276,197
– –
LUNG icon
57
Pulmonx
LUNG
$87.6M
$7.68M 0.18%
460,847
-230,408
-33% -$4.24M
RCOR
58
DELISTED
Renovacor, Inc.
RCOR
$7.56M 0.17%
3,000,803
– –
URGN icon
59
UroGen Pharma
URGN
$2.29B
$7.13M 0.16%
857,464
– –
TNYA icon
60
Tenaya Therapeutics
TNYA
$163M
$7.13M 0.16%
2,458,750
– –
SNCE
61
DELISTED
Science 37 Holdings, Inc. Common Stock
SNCE
$6.97M 0.16%
216,419
+2,042
+1% +$75.7K
RACB
62
DELISTED
Research Alliance Corp. II Class A Common Stock
RACB
$6.26M 0.14%
637,000
– –
BLSA
63
DELISTED
BCLS Acquisition Corp. Class A Ordinary Shares
BLSA
$6.14M 0.14%
612,500
– –
BWAY
64
Brainsway
BWAY
$622M
$5.79M 0.13%
3,204,762
– –
AKYA
65
DELISTED
Akoya BioSciences
AKYA
$5.68M 0.13%
483,815
+250,258
+107% +$3.3M
MASS icon
66
908 Devices
MASS
$364M
$5.13M 0.12%
312,000
-200,957
-39% -$3.9M
ARYD
67
DELISTED
ARYA Sciences Acquisition Corp IV Class A Odinary Shares
ARYD
$4.96M 0.11%
500,000
– –
SMIHU
68
DELISTED
Summit Healthcare Acquisition Corp. Units
SMIHU
$4.92M 0.11%
500,000
– –
ARYE
69
DELISTED
ARYA Sciences Acquisition Corp V Class A Ordinary Shares
ARYE
$4.9M 0.11%
500,000
– –
SGHT icon
70
Sight Sciences
SGHT
$412M
$4.22M 0.1%
665,323
-331,776
-33% -$2.81M
FVAM
71
DELISTED
5:01 Acquisition Corp
FVAM
$3.92M 0.09%
392,000
– –
MLTX icon
72
MoonLake Immunotherapeutics
MLTX
$1.55B
$3.88M 0.09%
500,000
– –
IMTX icon
73
Immatics
IMTX
$1.32B
$3.5M 0.08%
350,000
– –
TELA icon
74
TELA Bio
TELA
$38.9M
$3.33M 0.08%
390,364
-627,182
-62% -$5.2M
MSAC
75
DELISTED
Medicus Sciences Acquisition Corp. Class A Ordinary Share
MSAC
$2.97M 0.07%
300,000
– –
1 2
3
4 5

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RTW Investments's Q3 2022 Portfolio in Review

As of Q3 2022, RTW Investments held 111 positions worth $4.34B, up 12% from $3.87B the previous quarter. Its ten largest holdings account for 49% of the portfolio.

RTW Investments's Q3 2022 filing shows 4 new, 17 increased, 21 reduced and 25 closed positions. Its largest new stake was IVERIC bio, Inc. Common Stock: 3,625,000 shares worth $65M. The largest sale was Tandem Diabetes Care, an estimated $32.9M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 99% a quarter earlier, followed by Financials and Industrials.

  • RTW Investments's largest Q3 2022 buy was IVERIC bio, Inc. Common Stock: 3,625,000 shares worth $65M.
  • RTW Investments added most to Ultragenyx Pharmaceutical in Q3 2022, an estimated $50.7M increase.
  • RTW Investments's biggest Q3 2022 reduction was Tandem Diabetes Care, cutting an estimated $32.9M.
  • RTW Investments fully exited Quanterix in Q3 2022, selling an estimated $29.5M.
  • RTW Investments's ten largest holdings make up 49% of its $4.34B portfolio in Q3 2022.
  • RTW Investments opened 4 new positions and closed 25 in Q3 2022.
  • RTW Investments's portfolio value rose 12% quarter-over-quarter to $4.34B.

Based on RTW Investments's 13F filing for Q3 2022, filed 14 Nov 2022.