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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
-17.44%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$3.87B
AUM Growth
-$961M
Cap. Flow
+$318M
Cap. Flow %
8.21%
Top 10 Hldgs %
45.33%
Holding
116
New
10
Increased
28
Reduced
12
Closed
9

Top Buys

Rank Stock Value
1
ACAD icon
Acadia Pharmaceuticals
ACAD
+$78.8M
2
IMCR icon
Immunocore
IMCR
+$69.4M
3
TMO icon
Thermo Fisher Scientific
TMO
+$34.4M
4
ARGX icon
argenx
ARGX
+$34M
5
MASI
Masimo
MASI
+$29.9M

Top Sells

Rank Stock Value
1
GMED icon
Globus Medical
GMED
+$36.9M
2
AXNX
Axonics, Inc. Common Stock
AXNX
+$30.9M
3
LONA
LeonaBio Inc
LONA
+$25.7M
4
ITOS
iTeos Therapeutics
ITOS
+$15.7M
5
VCEL icon
Vericel Corp
VCEL
+$14.6M

Sector Composition

Rank Sector Weight
1 Healthcare 98.86%
2 Financials 0.75%
3 Industrials 0.27%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
JNCE
51
DELISTED
Jounce Therapeutics, Inc. Common Stock
JNCE
$13.2M 0.34%
4,358,433
-321,979
-7% -$1.57M
GLUE icon
52
Monte Rosa Therapeutics
GLUE
$1.34B
$11.7M 0.3%
1,214,572
– –
MGNX icon
53
MacroGenics
MGNX
$257M
$11.7M 0.3%
3,975,554
– –
MASS icon
54
908 Devices
MASS
$364M
$10.6M 0.27%
512,957
+472,957
+1,182% +$7.95M
CYRX icon
55
CryoPort
CYRX
$762M
$10.4M 0.27%
+335,299
New +$8.92M
LUNG icon
56
Pulmonx
LUNG
$87.6M
$10.2M 0.26%
691,255
-107,000
-13% -$2.2M
ALGN icon
57
Align Technology
ALGN
$12.3B
$9.94M 0.26%
+42,000
New +$12.9M
CTKB icon
58
Cytek Biosciences
CTKB
$546M
$9.84M 0.25%
+916,838
New +$9.13M
CDXS icon
59
Codexis
CDXS
$158M
$9.63M 0.25%
+920,448
New +$11.5M
IMUX icon
60
Immunic
IMUX
$195M
$9.58M 0.25%
276,197
+5,646
+2% +$362K
SLGC
61
DELISTED
SomaLogic, Inc. Class A Common Stock
SLGC
$9.56M 0.25%
+2,114,830
New +$12.6M
TWST icon
62
Twist Bioscience
TWST
$7.25B
$9.44M 0.24%
+270,000
New +$9.56M
WHWK
63
Whitehawk Therapeutics
WHWK
$235M
$9.42M 0.24%
764,701
– –
SGHT icon
64
Sight Sciences
SGHT
$412M
$8.96M 0.23%
997,099
– –
OYST
65
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
$8.91M 0.23%
2,058,504
– –
SNCE
66
DELISTED
Science 37 Holdings, Inc. Common Stock
SNCE
$8.62M 0.22%
214,377
+12,410
+6% +$907K
EPIX
67
DELISTED
ESSA Pharma
EPIX
$8.31M 0.21%
2,637,192
– –
BWAY
68
Brainsway
BWAY
$622M
$7.74M 0.2%
3,204,762
– –
LJPC
69
DELISTED
La Jolla Pharmaceutical Company
LJPC
$7.42M 0.19%
2,327,403
– –
TELA icon
70
TELA Bio
TELA
$38.9M
$7.13M 0.18%
1,017,546
– –
URGN icon
71
UroGen Pharma
URGN
$2.29B
$7.02M 0.18%
857,464
– –
RACB
72
DELISTED
Research Alliance Corp. II Class A Common Stock
RACB
$6.22M 0.16%
637,000
– –
RCOR
73
DELISTED
Renovacor, Inc.
RCOR
$6.08M 0.16%
3,000,803
– –
BLSA
74
DELISTED
BCLS Acquisition Corp. Class A Ordinary Shares
BLSA
$6.06M 0.16%
612,500
– –
XGN icon
75
Exagen
XGN
$166M
$5.88M 0.15%
1,025,002
+34,859
+4% +$203K
1 2
3
4 5

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RTW Investments's Q2 2022 Portfolio in Review

As of Q2 2022, RTW Investments held 116 positions worth $3.87B, down 20% from $4.83B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments deployed $318M of net new capital in Q2 2022, opening 10 new positions and adding to 28 existing holdings. Its largest new stake was Acadia Pharmaceuticals: 4,224,109 shares worth $59.5M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, down from 99% a quarter earlier, followed by Financials and Industrials.

On the sell side, the largest reduction was Globus Medical, an estimated $36.9M trimmed.

  • RTW Investments's largest Q2 2022 buy was Acadia Pharmaceuticals: 4,224,109 shares worth $59.5M.
  • RTW Investments added most to Immunocore in Q2 2022, an estimated $69.4M increase.
  • RTW Investments's biggest Q2 2022 reduction was Globus Medical, cutting an estimated $36.9M.
  • RTW Investments fully exited LeonaBio Inc in Q2 2022, selling an estimated $25.7M.
  • RTW Investments's ten largest holdings make up 45% of its $3.87B portfolio in Q2 2022.
  • RTW Investments opened 10 new positions and closed 9 in Q2 2022.
  • RTW Investments's portfolio value fell 20% quarter-over-quarter to $3.87B.

Based on RTW Investments's 13F filing for Q2 2022, filed 15 Aug 2022.