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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+9.72%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$6.63B
AUM Growth
+$221M
Cap. Flow
-$85.5M
Cap. Flow %
-1.29%
Top 10 Hldgs %
45.03%
Holding
125
New
14
Increased
22
Reduced
8
Closed
12

Top Buys

Rank Stock Value
1
EPIX
ESSA Pharma
EPIX
+$80.5M
2
MASI
Masimo
MASI
+$52.8M
3
RGNX icon
Regenxbio
RGNX
+$48M
4
GHRS icon
GH Research
GHRS
+$44.3M
5
GH icon
Guardant Health
GH
+$41.5M

Top Sells

Rank Stock Value
1
CERN
Cerner Corp
CERN
+$128M
2
ARVN icon
Arvinas
ARVN
+$107M
3
IMVT icon
Immunovant
IMVT
+$102M
4
TBIO
Translate Bio, Inc. Common Stock
TBIO
+$72.3M
5
CRIS icon
Curis
CRIS
+$41M

Sector Composition

Rank Sector Weight
1 Healthcare 88.48%
2 Financials 0.38%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
OYST
51
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
$32M 0.48%
1,861,209
– –
JNJ icon
52
Johnson & Johnson
JNJ
$625B
$28.1M 0.42%
170,542
– –
ADVM
53
DELISTED
Adverum Biotechnologies
ADVM
$25.8M 0.39%
735,792
+894
+0.1% +$48.2K
GLUE icon
54
Monte Rosa Therapeutics
GLUE
$1.34B
$25.2M 0.38%
+1,214,572
New +$24.7M
MIST icon
55
Milestone Pharmaceuticals
MIST
$152M
$23.7M 0.36%
4,315,102
– –
TELA icon
56
TELA Bio
TELA
$38.9M
$22.4M 0.34%
1,392,434
+10,091
+0.7% +$138K
CLSD
57
DELISTED
Clearside Biomedical
CLSD
$20.5M 0.31%
280,451
– –
TRIL
58
DELISTED
Trillium Therapeutics Inc.
TRIL
$20.3M 0.31%
2,091,389
– –
LONA
59
LeonaBio Inc
LONA
$72.1M
$19.5M 0.29%
190,656
-74,599
-28% -$13M
ABUS icon
60
Arbutus Biopharma
ABUS
$915M
$18.1M 0.27%
5,978,355
– –
PMVP icon
61
PMV Pharmaceuticals
PMVP
$63.5M
$16.5M 0.25%
484,133
– –
BWAY
62
Brainsway
BWAY
$622M
$16.3M 0.25%
3,204,362
– –
BLU
63
DELISTED
BELLUS Health Inc.
BLU
$15.4M 0.23%
4,968,017
– –
NEO icon
64
NeoGenomics
NEO
$2.13B
$13.1M 0.2%
+311,111
New +$13.8M
CERE
65
DELISTED
Cerevel Therapeutics Holdings, Inc. Common Stock
CERE
$12.8M 0.19%
500,000
– –
XGN icon
66
Exagen
XGN
$166M
$12.3M 0.19%
821,414
-804,951
-49% -$12.3M
BMEA icon
67
Biomea Fusion
BMEA
$91.3M
$12.3M 0.19%
+830,794
New +$14.7M
INMD icon
68
InMode
INMD
$880M
$11.8M 0.18%
249,998
– –
CELL
69
DELISTED
PhenomeX Inc. Common Stock
CELL
$11.5M 0.17%
257,546
– –
IMUX icon
70
Immunic
IMUX
$195M
$11.3M 0.17%
92,081
– –
ASLN
71
DELISTED
ASLAN Pharmaceuticals Limited American Depositary Shares
ASLN
$10.7M 0.16%
81,250
– –
NAUT icon
72
Nautilus Biotechnolgy
NAUT
$115M
$10.4M 0.16%
1,100,000
+600,000
+120% +$6.5M
LJPC
73
DELISTED
La Jolla Pharmaceutical Company
LJPC
$9.96M 0.15%
2,327,903
– –
SNCE
74
DELISTED
Science 37 Holdings, Inc. Common Stock
SNCE
$9.75M 0.15%
48,750
+16,250
+50% +$3.3M
VINC
75
DELISTED
Vincerx Pharma, Inc. Common Stock
VINC
$9.74M 0.15%
37,500
+12,500
+50% +$3.81M
1 2
3
4 5

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VPIM
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MF
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RTW Investments's Q2 2021 Portfolio in Review

As of Q2 2021, RTW Investments held 125 positions worth $6.63B, up 3.5% from $6.41B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments's Q2 2021 filing shows 14 new, 22 increased, 8 reduced and 12 closed positions. Its largest new stake was GH Research: 2,168,957 shares worth $42.7M. The largest sale was Cerner Corp, an estimated $128M.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, up from 88% a quarter earlier, followed by Financials.

  • RTW Investments's largest Q2 2021 buy was GH Research: 2,168,957 shares worth $42.7M.
  • RTW Investments added most to ESSA Pharma in Q2 2021, an estimated $80.5M increase.
  • RTW Investments's biggest Q2 2021 reduction was Rocket Pharmaceuticals, cutting an estimated $31.5M.
  • RTW Investments fully exited Cerner Corp in Q2 2021, selling an estimated $128M.
  • RTW Investments's ten largest holdings make up 45% of its $6.63B portfolio in Q2 2021.
  • RTW Investments opened 14 new positions and closed 12 in Q2 2021.
  • RTW Investments's portfolio value rose 3.5% quarter-over-quarter to $6.63B.

Based on RTW Investments's 13F filing for Q2 2021, filed 13 Aug 2021.