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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+10.81%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$4.15B
AUM Growth
+$599M
Cap. Flow
+$538M
Cap. Flow %
12.94%
Top 10 Hldgs %
45.29%
Holding
99
New
22
Increased
37
Reduced
6
Closed
9

Top Buys

Rank Stock Value
1
ILMN icon
Illumina
ILMN
+$62M
2
IMVT icon
Immunovant
IMVT
+$53.9M
3
CYTK icon
Cytokinetics
CYTK
+$46.8M
4
LONA
LeonaBio Inc
LONA
+$44.6M
5
GH icon
Guardant Health
GH
+$42.9M

Top Sells

Rank Stock Value
1
WVE icon
Wave Life Sciences
WVE
+$24.9M
2
QTTB icon
Q32 Bio
QTTB
+$22.8M
3
STAA icon
STAAR Surgical
STAA
+$19M
4
NEO icon
NeoGenomics
NEO
+$13.8M
5
RPTX
Repare Therapeutics
RPTX
+$6.98M

Sector Composition

Rank Sector Weight
1 Healthcare 92.6%
2 Materials 0.36%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ABUS icon
51
Arbutus Biopharma
ABUS
$915M
$18.7M 0.45%
5,978,355
-890,926
-13% -$2.71M
PMVP icon
52
PMV Pharmaceuticals
PMVP
$63.5M
$17.8M 0.43%
+500,000
New +$18.4M
ALT icon
53
Altimmune
ALT
$599M
$17.6M 0.42%
+1,334,940
New +$26.7M
MDXG icon
54
MiMedx Group
MDXG
$633M
$17.2M 0.41%
2,700,320
– –
IMUX icon
55
Immunic
IMUX
$195M
$16.9M 0.41%
+91,250
New +$14.9M
APYX icon
56
Apyx Medical
APYX
$171M
$16M 0.38%
3,391,279
– –
AMRS
57
DELISTED
Amyris Inc.
AMRS
$15.1M 0.36%
5,161,347
+2,057,812
+66% +$7.54M
XGN icon
58
Exagen
XGN
$166M
$13.6M 0.33%
1,250,131
-5,000
-0.4% -$64.4K
AFIB
59
DELISTED
Acutus Medical Inc
AFIB
$13.5M 0.32%
+451,834
New +$13.7M
ODT
60
DELISTED
Odonate Therapeutics, Inc. Common Stock
ODT
$13.4M 0.32%
999,256
+518,229
+108% +$14.7M
GNMK
61
DELISTED
GenMark Diagnostics, Inc
GNMK
$10.8M 0.26%
762,994
-172,212
-18% -$2.63M
ARCT icon
62
Arcturus Therapeutics
ARCT
$211M
$10.8M 0.26%
+251,236
New +$12.5M
CTMX icon
63
CytomX Therapeutics
CTMX
$754M
$10.1M 0.24%
1,526,003
+11,527
+0.8% +$85.5K
LJPC
64
DELISTED
La Jolla Pharmaceutical Company
LJPC
$9.65M 0.23%
2,395,029
+20,077
+0.8% +$83.2K
BLU
65
DELISTED
BELLUS Health Inc.
BLU
$9.55M 0.23%
4,195,356
-1,774,874
-30% -$5.03M
ITMR
66
DELISTED
Itamar Medical Ltd. American Depository Shares
ITMR
$9.34M 0.22%
457,218
– –
FULC icon
67
Fulcrum Therapeutics
FULC
$297M
$9.12M 0.22%
+1,150,565
New +$13.9M
INMD icon
68
InMode
INMD
$880M
$9.04M 0.22%
500,000
– –
RGNX icon
69
Regenxbio
RGNX
$708M
$8.76M 0.21%
318,434
+2,406
+0.8% +$78.4K
ARGX icon
70
argenx
ARGX
$54.1B
$8.34M 0.2%
31,752
– –
PNT
71
DELISTED
POINT Biopharma Global Inc. Common Stock
PNT
$7.05M 0.17%
+490,000
New +$6.68M
TMDX icon
72
Transmedics
TMDX
$2.91B
$6.93M 0.17%
503,266
– –
LSACU
73
DELISTED
LifeSci Acquisition Corp. Unit 1 COM & 1 WT
LSACU
$6.8M 0.16%
500,000
– –
BWAY
74
Brainsway
BWAY
$622M
$6.46M 0.16%
2,214,840
– –
TNGX icon
75
Tango Therapeutics
TNGX
$4.41B
$6.22M 0.15%
+600,000
New +$6.13M
1 2
3
4

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RTW Investments's Q3 2020 Portfolio in Review

As of Q3 2020, RTW Investments held 99 positions worth $4.15B, up 17% from $3.55B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments deployed $538M of net new capital in Q3 2020, opening 22 new positions and adding to 37 existing holdings. Its largest new stake was Illumina: 179,900 shares worth $54.1M.

By sector, the portfolio is most concentrated in Healthcare at 93% of assets, up from 91% a quarter earlier, followed by Materials.

On the sell side, the largest reduction was Q32 Bio, an estimated $22.8M trimmed.

  • RTW Investments's largest Q3 2020 buy was Illumina: 179,900 shares worth $54.1M.
  • RTW Investments added most to Immunovant in Q3 2020, an estimated $53.9M increase.
  • RTW Investments's biggest Q3 2020 reduction was Q32 Bio, cutting an estimated $22.8M.
  • RTW Investments fully exited Wave Life Sciences in Q3 2020, selling an estimated $24.9M.
  • RTW Investments's ten largest holdings make up 45% of its $4.15B portfolio in Q3 2020.
  • RTW Investments opened 22 new positions and closed 9 in Q3 2020.
  • RTW Investments's portfolio value rose 17% quarter-over-quarter to $4.15B.

Based on RTW Investments's 13F filing for Q3 2020, filed 16 Nov 2020.