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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+10.81%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$4.15B
AUM Growth
+$599M
Cap. Flow
+$538M
Cap. Flow %
12.94%
Top 10 Hldgs %
45.29%
Holding
99
New
22
Increased
37
Reduced
6
Closed
9

Top Buys

Rank Stock Value
1
ILMN icon
Illumina
ILMN
+$62M
2
IMVT icon
Immunovant
IMVT
+$53.9M
3
CYTK icon
Cytokinetics
CYTK
+$46.8M
4
LONA
LeonaBio Inc
LONA
+$44.6M
5
GH icon
Guardant Health
GH
+$42.9M

Sector Composition

Rank Sector Weight
1 Healthcare 92.6%
2 Materials 0.36%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
KRRO icon
26
Korro Bio
KRRO
$195M
$47.3M 1.14%
49,230
+6,000
+14% +$6.44M
CLDX icon
27
Celldex Therapeutics
CLDX
$3.28B
$46.3M 1.11%
3,120,137
+510,137
+20% +$5.98M
LONA
28
LeonaBio Inc
LONA
$72.1M
$45.4M 1.09%
+266,891
New +$44.6M
ESTA icon
29
Establishment Labs
ESTA
$2.28B
$43M 1.03%
2,319,138
NSTG
30
DELISTED
NanoString Technologies, Inc.
NSTG
$42.3M 1.02%
947,134
CYTK icon
31
Cytokinetics
CYTK
$10.4B
$40.7M 0.98%
+2,000,000
New +$46.8M
OYST
32
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
$40.6M 0.98%
1,923,893
+14,533
+0.8% +$340K
CSTL icon
33
Castle Biosciences
CSTL
$979M
$38.3M 0.92%
743,642
-59,868
-7% -$2.66M
ISEE
34
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$37.6M 0.9%
6,663,439
+66,903
+1% +$319K
DMTK
35
DELISTED
DermTech, Inc. Common Stock
DMTK
$34.5M 0.83%
2,887,215
+31,450
+1% +$364K
MGNX icon
36
MacroGenics
MGNX
$257M
$31.6M 0.76%
1,255,299
+9,483
+0.8% +$259K
MIST icon
37
Milestone Pharmaceuticals
MIST
$152M
$31.6M 0.76%
4,315,102
TRIL
38
DELISTED
Trillium Therapeutics Inc.
TRIL
$30.7M 0.74%
+2,160,800
New +$21.5M
INCY icon
39
Incyte
INCY
$24.4B
$30M 0.72%
+334,144
New +$32.2M
AVDL
40
DELISTED
Avadel Pharmaceuticals
AVDL
$27M 0.65%
5,366,705
+60,135
+1% +$438K
QTTB icon
41
Q32 Bio
QTTB
$464M
$26.9M 0.65%
139,884
-101,904
-42% -$22.8M
OSUR icon
42
OraSure Technologies
OSUR
$279M
$25.3M 0.61%
2,075,082
+534,110
+35% +$7.3M
PRQR icon
43
ProQR Therapeutics
PRQR
$265M
$23.8M 0.57%
4,973,174
+70,389
+1% +$368K
VXRT
44
DELISTED
Vaxart
VXRT
$23.4M 0.56%
+3,517,345
New +$31.3M
CELL
45
DELISTED
PhenomeX Inc. Common Stock
CELL
$22.9M 0.55%
+300,338
New +$19.1M
TELA icon
46
TELA Bio
TELA
$38.9M
$22.8M 0.55%
1,378,776
+14,418
+1% +$202K
JNJ icon
47
Johnson & Johnson
JNJ
$625B
$22.3M 0.54%
149,761
+22,903
+18% +$3.39M
ITOS
48
DELISTED
iTeos Therapeutics
ITOS
$20.9M 0.5%
+902,855
New +$24.3M
ADAP
49
DELISTED
Adaptimmune Therapeutics
ADAP
$20.9M 0.5%
2,617,626
+17,626
+0.7% +$154K
OM icon
50
Outset Medical
OM
$90.8M
$20.3M 0.49%
+27,000
New +$22.2M

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RTW Investments's Q3 2020 Portfolio in Review

As of Q3 2020, RTW Investments held 99 positions worth $4.15B, up 17% from $3.55B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments deployed $538M of net new capital in Q3 2020, opening 22 new positions and adding to 37 existing holdings. Its largest new stake was Illumina: 179,900 shares worth $54.1M.

By sector, the portfolio is most concentrated in Healthcare at 93% of assets, up from 91% a quarter earlier, followed by Materials.

On the sell side, the largest reduction was Q32 Bio, an estimated $22.8M trimmed.

  • RTW Investments's largest Q3 2020 buy was Illumina: 179,900 shares worth $54.1M.
  • RTW Investments added most to Immunovant in Q3 2020, an estimated $53.9M increase.
  • RTW Investments's biggest Q3 2020 reduction was Q32 Bio, cutting an estimated $22.8M.
  • RTW Investments fully exited Wave Life Sciences in Q3 2020, selling an estimated $24.9M.
  • RTW Investments's ten largest holdings make up 45% of its $4.15B portfolio in Q3 2020.
  • RTW Investments opened 22 new positions and closed 9 in Q3 2020.
  • RTW Investments's portfolio value rose 17% quarter-over-quarter to $4.15B.

Based on RTW Investments's 13F filing for Q3 2020, filed 16 Nov 2020.