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OM
Opaleye Management Portfolio holdings
AUM
$758M
1-Year Est. Return
124.8%
This Fund
S&P 500
This Quarter
Est. Return
+47.1%
1 Year Est. Return
+124.8%
3 Year Est. Return
+486.05%
5 Year Est. Return
+742.19%
10 Year Est. Return
+62,231.09%
AUM
$707M
AUM Growth
+$213M
(+43%)
Cap. Flow
+$10.5M
Cap. Flow
% of AUM
1.48%
Top 10 Holdings %
Top 10 Hldgs %
72.97%
Holding
52
New
11
Increased
9
Reduced
11
Closed
8
Top Buys
| 1 |
Apogee Therapeutics
APGE
|
+$13.9M |
| 2 |
Alkermes
ALKS
|
+$12.7M |
| 3 |
Annexon
ANNX
|
+$6.46M |
| 4 |
Journey Medical
DERM
|
+$6.35M |
| 5 |
Treace Medical Concepts
TMCI
|
+$4.59M |
Top Sells
| 1 |
VIGL
Vigil Neuroscience
VIGL
|
+$7.95M |
| 2 |
Anika Therapeutics
ANIK
|
+$6.23M |
| 3 |
Ginkgo Bioworks
DNA
|
+$5.63M |
| 4 |
Arvinas
ARVN
|
+$5.25M |
| 5 |
EPIX
ESSA Pharma
EPIX
|
+$3.76M |
Sector Composition
| 1 | Healthcare | 99.35% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
26
Protalix BioTherapeutics
PLX
$186M
| $5.73M | 0.81% |
+2,580,556
| New | +$4.2M |
|
|
27
Treace Medical Concepts
TMCI
$288M
| $4.71M | 0.67% |
+702,245
| New | +$4.59M |
|
28
Revolution Medicines
RVMD
$39.3B
| $4.67M | 0.66% |
100,000
-5,000
| -5% | -$196K |
|
|
MBX
29
MBX Biosciences
MBX
$2.69B
| $4.43M | 0.63% |
253,000
+13,681
| +6% | +$183K |
|
30
Trevi Therapeutics
TRVI
$2.54B
| $3.57M | 0.5% |
390,000
| – | – |
|
31
ADC Therapeutics
ADCT
$156M
| $2.73M | 0.39% |
+682,529
| New | +$2.15M |
|
|
ALMS
32
Alumis Inc
ALMS
$3.48B
| $2.65M | 0.38% |
665,000
-110,000
| -14% | -$453K |
|
33
Cabaletta Bio
CABA
$435M
| $1.89M | 0.27% |
+808,882
| New | +$1.39M |
|
|
IRD
34
Opus Genetics
IRD
$294M
| $1.81M | 0.26% |
1,100,000
-120,000
| -10% | -$149K |
|
35
Zymeworks
ZYME
$1.81B
| $1.71M | 0.24% |
100,000
-110,000
| -52% | -$1.57M |
|
36
Spyre Therapeutics
SYRE
$8.59B
| $1.09M | 0.15% |
+65,000
| New | +$1.06M |
|
37
Rigel Pharmaceuticals
RIGL
$762M
| $1.07M | 0.15% |
+37,787
| New | +$1.13M |
|
|
ACOG
38
Alpha Cognition
ACOG
$175M
| $750K | 0.11% |
+115,142
| New | +$1.05M |
|
39
Zentalis Pharmaceuticals
ZNTL
$340M
| $478K | 0.07% |
316,550
-1,607,750
| -84% | -$2.41M |
|
40
PepGen
PEPG
$169M
| $347K | 0.05% |
75,000
-165,000
| -69% | -$266K |
|
41
iBio
IBIO
$71.5M
| $310K | 0.04% |
375,000
| – | – |
|
|
ADGM
42
Adagio Medical Holdings
ADGM
$12.9M
| $215K | 0.03% |
110,571
| – | – |
|
|
43
Anika Therapeutics
ANIK
$207M
| – | – |
-588,797
| Closed | -$6.23M |
|
|
CRGX
44
DELISTED
CARGO Therapeutics
CRGX
| – | – |
-666,503
| Closed | -$2.75M |
|
|
45
Ginkgo Bioworks
DNA
$591M
| – | – |
-500,000
| Closed | -$5.63M |
|
|
ELEV
46
DELISTED
Elevation Oncology
ELEV
| – | – |
-1,442,061
| Closed | -$529K |
|
|
EPIX
47
DELISTED
ESSA Pharma
EPIX
| – | – |
-2,209,998
| Closed | -$3.76M |
|
48
Avita Medical
RCEL
$124M
| – | – |
-389,519
| Closed | -$2.06M |
|
49
Protara Therapeutics
TARA
$230M
| – | – |
-855,000
| Closed | -$2.59M |
|
|
VIGL
50
DELISTED
Vigil Neuroscience
VIGL
| – | – |
-1,000,000
| Closed | -$7.95M |
|
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