OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+6.78%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.29%
AUM
$150M
AUM Growth
+$150M
Cap. Flow
-$10.5M
Cap. Flow %
-6.99%
Top 10 Hldgs %
46.24%
Holding
65
New
13
Increased
10
Reduced
12
Closed
16

Top Buys

1
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$3.29M
2
MGNX icon
MacroGenics
MGNX
$3.02M
3
GBT
Global Blood Therapeutics, Inc.
GBT
$2.52M
4
GNMX
Aevi Genomic Medicine, Inc.
GNMX
$2.18M
5
IOVA icon
Iovance Biotherapeutics
IOVA
$2.11M

Top Sells

1
SAGE
Sage Therapeutics
SAGE
$5.29M
2
ASRT icon
Assertio
ASRT
$4.53M
3
GERN icon
Geron
GERN
$3.87M
4
ISEE
IVERIC bio, Inc. Common Stock
ISEE
$3.38M
5
AMAG
AMAG Pharmaceuticals, Inc.
AMAG
$2.39M

Sector Composition

1 Healthcare 83.76%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
AXGN icon
1
Axogen
AXGN
$743M
$14.6M 9.74% 2,120,000 – –
GNMX
2
DELISTED
Aevi Genomic Medicine, Inc.
GNMX
$10.8M 7.23% 1,950,000 +392,300 +25% +$2.18M
ARIA
3
DELISTED
Ariad Pharmaceuticals Inc
ARIA
$9.24M 6.17% 1,250,000 – –
FGEN icon
4
FibroGen
FGEN
$47.8M
$5.42M 3.62% 330,000 +5,000 +2% +$82K
BPMC
5
DELISTED
Blueprint Medicines
BPMC
$5.06M 3.38% 250,000 +30,000 +14% +$608K
HROW icon
6
Harrow
HROW
$1.44B
$4.77M 3.18% 1,267,500 +17,500 +1% +$65.8K
CDXS icon
7
Codexis
CDXS
$246M
$4.75M 3.17% 1,178,500 – –
ADMS
8
DELISTED
Adamas Pharmaceuticals, Inc.
ADMS
$4.54M 3.03% 300,000 -20,000 -6% -$303K
FOMX
9
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
$4.41M 2.95% 695,000 +105,000 +18% +$667K
TVRD
10
Tvardi Therapeutics, Inc. Common Stock
TVRD
$281M
$4.02M 2.68% 835,000 -20,000 -2% -$96.2K
AMRN
11
Amarin Corp
AMRN
$311M
$3.8M 2.54% 1,760,000 – –
AGIO icon
12
Agios Pharmaceuticals
AGIO
$2.19B
$3.56M 2.38% 85,000 -20,000 -19% -$838K
HZNP
13
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$3.29M 2.2% +200,000 New +$3.29M
RARE icon
14
Ultragenyx Pharmaceutical
RARE
$2.89B
$3.18M 2.12% 65,000 -45,000 -41% -$2.2M
MGNX icon
15
MacroGenics
MGNX
$112M
$3.02M 2.02% +112,000 New +$3.02M
IMMU
16
DELISTED
Immunomedics Inc
IMMU
$3.02M 2.01% 1,300,000 -25,000 -2% -$58K
INDP icon
17
Indaptus Therapeutics
INDP
$7.19M
$2.99M 2% 650,000 +12,000 +2% +$55.2K
AMAG
18
DELISTED
AMAG Pharmaceuticals, Inc.
AMAG
$2.87M 1.92% 120,000 -100,000 -45% -$2.39M
CMRX
19
DELISTED
Chimerix, Inc.
CMRX
$2.65M 1.77% 675,000 – –
SUPN icon
20
Supernus Pharmaceuticals
SUPN
$2.53B
$2.55M 1.7% 125,000 – –
GBT
21
DELISTED
Global Blood Therapeutics, Inc.
GBT
$2.52M 1.68% +152,000 New +$2.52M
XENE icon
22
Xenon Pharmaceuticals
XENE
$2.98B
$2.42M 1.62% 410,000 +10,000 +3% +$59K
PDSB icon
23
PDS Biotechnology
PDSB
$57.8M
$2.28M 1.52% 225,600 +40,600 +22% +$410K
IOVA icon
24
Iovance Biotherapeutics
IOVA
$807M
$2.11M 1.41% +260,000 New +$2.11M
CYNA
25
DELISTED
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR (CANADA)
CYNA
$2.09M 1.4% 125,000 +4,000 +3% +$67K
1
2 3