Opaleye Management’s IVERIC bio, Inc. Common Stock ISEE Stock Holding History

Opaleye Management’s Portfolio ISEE Stock Details ISEE Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2016 Q2	–	Sell	-80,000	Closed	-$3.38M	–	60
2016 Q1	$3.38M	Sell	80,000 -25,000	-24%	-$1.27M	2.11%	22
2015 Q4	$8.25M	Hold	105,000	–	–	3.45%	8
2015 Q3	$4.25M	Hold	105,000	–	–	2.09%	21
2015 Q2	$5.49M	Hold	105,000	–	–	2.18%	19
2015 Q1	$4.89M	Buy	105,000 +5,000	+5%	+$260K	2.27%	21
2014 Q4	$4.49M	Buy	100,000 +65,000	+186%	+$2.73M	2.27%	15
2014 Q3	$1.36M	Buy	+35,000	New	+$1.37M	1.06%	27

Other funds holding ISEE

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

NHAS

Novo Holdings A/S Hellerup, Denmark $1.72B AUM 106.92% 1-Year Est. Return

JCG

JHL Capital Group Chicago, Illinois $805M AUM 50.84% 1-Year Est. Return

Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return

BFA

BlackRock Fund Advisors San Francisco, California $542B AUM 18.13% 1-Year Est. Return

EAM

Eagle Asset Management St Petersburg, Florida $19.6B AUM 41.58% 1-Year Est. Return

State Street Boston, Massachusetts $3.38T AUM 44.17% 1-Year Est. Return

Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return

Opaleye Management's ISEE Position: Q2 2016 in Review

Opaleye Management sold out of IVERIC bio, Inc. Common Stock (ISEE) in Q2 2016, closing a stake of 80,000 shares — an estimated $3.38M sold.

Opaleye Management first reported a position in ISEE in Q3 2014 and held it in 7 quarters. The position peaked at $8.25M in Q4 2015. 182 funds tracked by Wall St. Rank hold ISEE as of Q2 2016.

Opaleye Management reported no remaining IVERIC bio, Inc. Common Stock position as of Q2 2016 after selling out during the quarter.
Opaleye Management sold 80,000 IVERIC bio, Inc. Common Stock shares in Q2 2016, an estimated $3.38M.
Opaleye Management first reported a position in IVERIC bio, Inc. Common Stock in Q3 2014 and held it in 7 quarters.
Opaleye Management's IVERIC bio, Inc. Common Stock position peaked at $8.25M in Q4 2015.
182 funds tracked by Wall St. Rank held IVERIC bio, Inc. Common Stock as of Q2 2016.

Based on Opaleye Management's 13F filing for Q2 2016, filed 12 Aug 2016.