OM
EPIX

Opaleye Management’s ESSA Pharma EPIX Stock Holding History

Opaleye Management’s Portfolio EPIX Stock Details EPIX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-2,209,998
Closed -$3.76M – 48
2025
Q2 		$3.76M Hold
2,209,998
– – 0.76% 27
2025
Q1 		$3.49M Hold
2,209,998
– – 0.78% 28
2024
Q4 		$3.96M Buy
+2,209,998
New +$7.04M 0.69% 28
2021
Q3 		– Sell
-284,050
Closed -$8.12M – 51
2021
Q2 		$8.12M Hold
284,050
– – 1.35% 24
2021
Q1 		$8.25M Hold
284,050
– – 1.21% 23
2020
Q4 		$3.39M Buy
284,050
+12,700
+5% +$89.4K 0.44% 47
2020
Q3 		$1.87M Buy
271,350
+96,350
+55% +$654K 0.37% 45
2020
Q2 		$1.08M Buy
+175,000
New +$830K 0.22% 44

Other funds holding EPIX

BI
BVF Inc San Francisco, California $3.91B AUM 304.52% 1-Year Est. Return
SCM
Soleus Capital Management Greenwich, Connecticut $2.9B AUM 169.69% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return
P
Pfizer New York $170M AUM 191.09% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.55T AUM 33.47% 1-Year Est. Return
LP
LMR Partners London, United Kingdom $26.8B AUM 68.38% 1-Year Est. Return
SC
Shay Capital New York $1.56B AUM 46.17% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
Two Sigma Advisers
Two Sigma Advisers New York $51.4B AUM 31.07% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $875B AUM 40.91% 1-Year Est. Return

Opaleye Management's EPIX Position: Q3 2025 in Review

Opaleye Management sold out of ESSA Pharma (EPIX) in Q3 2025, closing a stake of 2,209,998 shares — an estimated $3.76M sold.

Opaleye Management first reported a position in EPIX in Q2 2020 and held it in 8 quarters. The position peaked at $8.25M in Q1 2021. 32 funds tracked by Wall St. Rank hold EPIX as of Q3 2025.

  • Opaleye Management reported no remaining ESSA Pharma position as of Q3 2025 after selling out during the quarter.
  • Opaleye Management sold 2,209,998 ESSA Pharma shares in Q3 2025, an estimated $3.76M.
  • Opaleye Management first reported a position in ESSA Pharma in Q2 2020 and held it in 8 quarters.
  • Opaleye Management's ESSA Pharma position peaked at $8.25M in Q1 2021.
  • 32 funds tracked by Wall St. Rank held ESSA Pharma as of Q3 2025.

Based on Opaleye Management's 13F filing for Q3 2025, filed 14 Nov 2025.