Opaleye Management’s Zymeworks ZYME Stock Holding History

Quarter	Market Value	Status	Shares	Shares Change %	Trade Value	Portfolio Weight	Portfolio Position
2025 Q2	$2.64M	Buy	210,000 +35,000	+20%	+$439K	0.53%	30
2025 Q1	$2.08M	Buy	+175,000	New	+$2.08M	0.46%	31
2020 Q2	–	Sell	-133,000	Closed	-$4.72M	–	53
2020 Q1	$4.72M	Sell	133,000 -42,000	-24%	-$1.49M	1.25%	27
2019 Q4	$7.96M	Buy	175,000 +5,000	+3%	+$227K	1.56%	29
2019 Q3	$4.22M	Hold	170,000	–	–	1.52%	27
2019 Q2	$3.74M	Buy	170,000 +115,000	+209%	+$2.53M	1.14%	30
2019 Q1	$890K	Sell	55,000 -50,000	-48%	-$809K	0.25%	48
2018 Q4	$1.54M	Buy	+105,000	New	+$1.54M	0.58%	37