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Opaleye Management’s PepGen PEPG Stock Holding History

Opaleye Management’s Portfolio PEPG Stock Details PEPG Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-75,000
Closed -$347K – 60
2025
Q3 		$347K Sell
75,000
-165,000
-69% -$266K 0.05% 41
2025
Q2 		$266K Sell
240,000
-180,000
-43% -$255K 0.05% 40
2025
Q1 		$590K Buy
420,000
+310,000
+282% +$638K 0.13% 42
2024
Q4 		$417K Sell
110,000
-69,200
-39% -$431K 0.07% 37
2024
Q3 		$1.53M Buy
+179,200
New +$2.12M 0.26% 38

Other funds holding PEPG

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
Viking Global Investors
Viking Global Investors Stamford, Connecticut $35.1B AUM 21.36% 1-Year Est. Return
CC
Commodore Capital New York $1.68B AUM 375.52% 1-Year Est. Return
VC
Vivo Capital Palo Alto, California $1.1B AUM 799.93% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $90.7B AUM 77.13% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
LCM
Laurion Capital Management New York $3.9B AUM 75.03% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.91B AUM 304.52% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $3.01B AUM 119.46% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London $209B AUM 37.72% 1-Year Est. Return

Opaleye Management's PEPG Position: Q4 2025 in Review

Opaleye Management sold out of PepGen (PEPG) in Q4 2025, closing a stake of 75,000 shares — an estimated $347K sold.

Opaleye Management first reported a position in PEPG in Q3 2024 and held it in 5 quarters. The position peaked at $1.53M in Q3 2024. 87 funds tracked by Wall St. Rank hold PEPG as of Q4 2025.

  • Opaleye Management reported no remaining PepGen position as of Q4 2025 after selling out during the quarter.
  • Opaleye Management sold 75,000 PepGen shares in Q4 2025, an estimated $347K.
  • Opaleye Management first reported a position in PepGen in Q3 2024 and held it in 5 quarters.
  • Opaleye Management's PepGen position peaked at $1.53M in Q3 2024.
  • 87 funds tracked by Wall St. Rank held PepGen as of Q4 2025.

Based on Opaleye Management's 13F filing for Q4 2025, filed 17 Feb 2026.