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PepGen
PEPG

52 hedge funds and large institutions have $25.8M invested in PepGen in 2025 Q2 according to their latest regulatory filings, with 5 funds opening new positions, 17 increasing their positions, 20 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

6.45% less ownership

Funds ownership: 77.45% → 70.99% (-6.5%)

15% less repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 20

28% less capital invested

Capital invested by funds: $35.6M → $25.8M (-$9.79M)

28% less funds holding

Funds holding: 72 → 52 (-20)

80% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 25

Holders
52
Holders Change
-20
Holders Change %
-27.78%
% of All Funds
0.68%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
5
Increased
17
Reduced
20
Closed
25
Calls
$12K
Puts
–
Net Calls
+$12K
Net Calls Change
+$92K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$673K
2
PM
Prosight Management
Texas
+$345K
3
SFM
Sphera Funds Management
Israel
+$221K
4
RC
RBF Capital
California
+$141K
5
Point72 Asset Management
Point72 Asset Management
Connecticut
+$118K

Top Sellers

Rank Fund Capital Flow
1
SCM
Suvretta Capital Management
New York
-$1.92M
2
BlackRock
BlackRock
New York
-$914K
3
State Street
State Street
Massachusetts
-$355K
4
Geode Capital Management
Geode Capital Management
Massachusetts
-$258K
5
OM
Opaleye Management
Massachusetts
-$255K
Name Holding Trade Value Shares
Change 		Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$11.9M – – –
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$3.06M +$118K +83,234 +3%
Millennium Management
3
Millennium Management
New York
$1.68M +$673K +476,180 +46%
Viking Global Investors
4
Viking Global Investors
Connecticut
$1.65M – – –
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$1.5M – – –
Vanguard Group
6
Vanguard Group
Pennsylvania
$1.04M +$52.7K +37,289 +4%
LCM
7
Laurion Capital Management
New York
$900K – – –
WP
8
Woodline Partners
California
$768K -$126K -89,367 -11%
BlackRock
9
BlackRock
New York
$719K -$914K -646,232 -50%
SCM
10
Suvretta Capital Management
New York
$333K -$1.92M -1,360,932 -82%
PM
11
Prosight Management
Texas
$271K +$345K +243,980 New
OM
12
Opaleye Management
Massachusetts
$266K -$255K -180,000 -43%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$223K -$258K -182,797 -48%
SFM
14
Sphera Funds Management
Israel
$174K +$221K +156,467 New
IC
15
Ikarian Capital
Texas
$167K – – –
RC
16
RBF Capital
California
$111K +$141K +100,000 New
BCM
17
Bridgeway Capital Management
Texas
$102K +$49.5K +35,000 +61%
Qube Research & Technologies (QRT)
18
Qube Research & Technologies (QRT)
United Kingdom
$81K +$103K +73,004 New
Goldman Sachs
19
Goldman Sachs
New York
$78.4K +$42.9K +30,363 +75%
State Street
20
State Street
Massachusetts
$76.7K -$355K -250,963 -78%
Morgan Stanley
21
Morgan Stanley
New York
$72K +$45 +32 +0%
Two Sigma Investments
22
Two Sigma Investments
New York
$70.8K +$24.8K +17,546 +38%
Renaissance Technologies
23
Renaissance Technologies
New York
$56.9K +$8.48K +6,000 +13%
Northern Trust
24
Northern Trust
Illinois
$53.3K -$132K -93,053 -66%
BFM
25
Boothbay Fund Management
New York
$50.6K – – –
1
2 3 4

PEPG Hedge Fund Activity: Q2 2025 in Review

52 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in PepGen (PEPG) for Q2 2025, worth a combined $25.8M — down 28% from $35.6M a quarter earlier.

Sellers outnumbered buyers: 25 funds closed out of PEPG and 5 opened new positions — a net loss of 20 holders — while 20 trimmed existing stakes and 17 added.

The largest buyer was Millennium Management, adding an estimated $673K. The largest seller was Suvretta Capital Management, cutting an estimated $1.92M.

  • 52 institutional investors held PepGen (PEPG) as of Q2 2025, down from 72 in Q1 2025.
  • Funds reported $25.8M of PepGen stock for Q2 2025, down 28% quarter-over-quarter.
  • 5 funds opened new PepGen positions in Q2 2025 and 25 closed out, a net change of -20 holders.
  • The largest PepGen buyer in Q2 2025 was Millennium Management, an estimated $673K added.
  • The largest PepGen seller in Q2 2025 was Suvretta Capital Management, an estimated $1.92M sold.

Based on aggregated 13F filings for Q2 2025.