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PepGen

72 hedge funds and large institutions have $262M invested in PepGen in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 19 increasing their positions, 19 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

916% more capital invested

Capital invested by funds: $25.8M → $262M (+$236M)

597% more call options, than puts

Call options by funds: $5.9M | Put options by funds: $846K

167% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 12

101.96% more ownership

Funds ownership: 70.99%172.95% (+102%)

38% more funds holding

Funds holding: 5272 (+20)

0% more repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 19

Holders
72
Holders Change
+20
Holders Change %
+38.46%
% of All Funds
0.94%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
32
Increased
19
Reduced
19
Closed
12
Calls
$5.9M
Puts
$846K
Net Calls
+$5.05M
Net Calls Change
+$5.04M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$92.7M +$15.1M +9,375,000 +88%
Viking Global Investors
2
Viking Global Investors
Connecticut
$16.1M +$3.22M +2,000,000 +135%
CC
3
Commodore Capital
New York
$10.9M +$3.8M +2,357,319 New
VC
4
Vivo Capital
California
$10.7M +$3.75M +2,325,000 New
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$9.38M -$1.18M -729,171 -26%
BI
6
BVF Inc
California
$8.85M +$3.09M +1,915,000 New
LCM
7
Laurion Capital Management
New York
$8.74M +$1.74M +1,081,395 +133%
Vanguard Group
8
Vanguard Group
Pennsylvania
$8.17M +$1.34M +831,333 +89%
RI
9
RTW Investments
New York
$6.93M +$2.42M +1,500,000 New
Janus Henderson Group
10
Janus Henderson Group
United Kingdom
$6.92M +$2.42M +1,500,000 New
Adage Capital Partners
11
Adage Capital Partners
Massachusetts
$6.7M +$161K +100,000 +7%
Balyasny Asset Management
12
Balyasny Asset Management
Illinois
$6.16M +$2.15M +1,333,583 New
WP
13
Woodline Partners
California
$6.06M +$999K +619,491 +90%
DTC
14
Deep Track Capital
Connecticut
$5.54M +$1.93M +1,200,000 New
TCM
15
TCG Crossover Management
California
$5.54M +$1.93M +1,200,000 New
AIC
16
AWM Investment Company
New York
$4.74M +$1.65M +1,025,000 New
PA
17
Perceptive Advisors
New York
$3.83M +$1.34M +829,870 New
EC
18
EcoR1 Capital
California
$3.7M +$1.29M +800,000 New
LGM
19
Logos Global Management
California
$3.46M +$1.21M +750,000 New
OCA
20
Octagon Capital Advisors
New York
$3.23M +$1.13M +700,000 New
SL
21
Siren LLC
Connecticut
$3.23M +$1.13M +700,000 New
Morgan Stanley
22
Morgan Stanley
New York
$2.66M +$823K +510,318 +787%
IC
23
Ikarian Capital
Texas
$2.48M +$622K +385,967 +257%
Millennium Management
24
Millennium Management
New York
$2.31M -$1.63M -1,008,932 -67%
Pictet Asset Management
25
Pictet Asset Management
Switzerland
$2.22M +$776K +481,365 New

PEPG Hedge Fund Activity: Q3 2025 in Review

72 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in PepGen (PEPG) for Q3 2025, worth a combined $262M — up 916% from $25.8M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new PEPG positions and 12 closed out — a net gain of 20 holders — while 19 added to existing stakes and 19 trimmed.

The largest buyer was RA Capital Management, adding an estimated $15.1M. The largest seller was Millennium Management, cutting an estimated $1.63M.

  • 72 institutional investors held PepGen (PEPG) as of Q3 2025, up from 52 in Q2 2025.
  • Funds reported $262M of PepGen stock for Q3 2025, up 916% quarter-over-quarter.
  • 32 funds opened new PepGen positions in Q3 2025 and 12 closed out, a net change of +20 holders.
  • The largest PepGen buyer in Q3 2025 was RA Capital Management, an estimated $15.1M added.
  • The largest PepGen seller in Q3 2025 was Millennium Management, an estimated $1.63M sold.

Based on aggregated 13F filings for Q3 2025.