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NLVP

New Leaf Venture Partners Portfolio holdings

AUM $43M
1-Year Est. Return 25.55%
This Fund
S&P 500
This Quarter Est. Return
-4.11%
1 Year Est. Return
-25.55%
3 Year Est. Return
+17.13%
5 Year Est. Return
+114.46%
10 Year Est. Return
+1,011.57%
AUM
$347M
AUM Growth
-$42.9M
Cap. Flow
-$20.7M
Cap. Flow %
-5.98%
Top 10 Hldgs %
88.65%
Holding
23
New
4
Increased
–
Reduced
1
Closed
1
Avg Time Held
9.1 quarters
Top 10 Avg Time Held
4.6 quarters
Top 20 Avg Time Held
9.4 quarters

Top Buys

Rank Stock Value
1
RLYB icon
Rallybio
RLYB
+$33.7M
2
DICE icon
DICE Therapeutics, Inc. Common Stock
DICE
+$19M
3
RCOR
Renovacor, Inc.
RCOR
+$6.8M
4
AMYT
Amryt Pharma plc American Depositary Shares
AMYT
+$5.08M

Top Sells

Rank Stock Value
1
ARVN icon
Arvinas
ARVN
+$79.9M
2
CHMA
Chiasma, Inc. Common Stock
CHMA
+$5.37M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow Held Since
ARVN icon
1
Arvinas
ARVN
$496M
$108M 31.01%
1,308,187
-904,561
-41% -$79.9M
2018 Q3
12 quarters
DCPH icon
2
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$41.1M 11.86%
1,209,571
– –
2017 Q3
16 quarters
RLYB icon
3
Rallybio
RLYB
$90.7M
$40.5M 11.67%
+287,700
New +$33.7M
2021 Q3
0 quarters
EWTX icon
4
Edgewise Therapeutics
EWTX
$4.21B
$25.8M 7.44%
1,553,661
– –
2021 Q1
2 quarters
HARP
5
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
$24.9M 7.19%
315,670
– –
2019 Q1
10 quarters
PASG icon
6
Passage Bio
PASG
$11.9M
$24.9M 7.18%
124,896
– –
2020 Q1
6 quarters
DICE icon
7
DELISTED
DICE Therapeutics, Inc. Common Stock
DICE
$18.2M 5.26%
+556,693
New +$19M
2021 Q3
0 quarters
SRRA
8
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$8.98M 2.59%
409,611
– –
2017 Q1
18 quarters
ALEC icon
9
Alector
ALEC
$230M
$7.75M 2.24%
339,569
– –
2019 Q1
10 quarters
APTX
10
DELISTED
Aptinyx Inc. Common Stock
APTX
$7.7M 2.22%
3,290,079
– –
2018 Q2
13 quarters
CMRX icon
11
DELISTED
Chimerix, Inc.
CMRX
$7.58M 2.19%
1,224,600
– –
2018 Q3
12 quarters
RCOR
12
DELISTED
Renovacor, Inc.
RCOR
$6.31M 1.82%
+697,436
New +$6.8M
2021 Q3
0 quarters
AMYT
13
DELISTED
Amryt Pharma plc American Depositary Shares
AMYT
$5.42M 1.56%
+449,737
New +$5.08M
2021 Q3
0 quarters
COGT icon
14
Cogent Biosciences
COGT
$5.32B
$4.22M 1.22%
501,530
– –
2018 Q1
14 quarters
ARAV
15
DELISTED
Aravive, Inc. Common Stock
ARAV
$3.52M 1.02%
946,423
– –
2018 Q2
13 quarters
CRNX icon
16
DELISTED
Crinetics Pharmaceuticals
CRNX
$2.97M 0.86%
141,000
– –
2018 Q3
12 quarters
OBSV
17
DELISTED
ObsEva SA Ordinary Shares
OBSV
$2.8M 0.81%
900,501
– –
2017 Q1
18 quarters
XFOR icon
18
X4 Pharmaceuticals
XFOR
$288M
$1.77M 0.51%
11,167
– –
2019 Q2
9 quarters
TECX icon
19
Tectonic Therapeutic
TECX
$442M
$1.76M 0.51%
26,296
– –
2018 Q2
13 quarters
PDSB icon
20
PDS Biotechnology
PDSB
$104M
$1.75M 0.5%
117,242
– –
2019 Q2
9 quarters
ITRM icon
21
DELISTED
Iterum Therapeutics
ITRM
$813K 0.23%
97,087
– –
2018 Q2
13 quarters
ADXN icon
22
Addex Therapeutics
ADXN
$5.61M
$451K 0.13%
2,500
– –
2021 Q2
1 quarter
CHMA
23
DELISTED
Chiasma, Inc. Common Stock
CHMA
– –
-1,135,700
Closed -$5.37M –

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New Leaf Venture Partners's Q3 2021 Portfolio in Review

As of Q3 2021, New Leaf Venture Partners held 23 positions worth $347M, down 11% from $390M the previous quarter. Its ten largest holdings account for 89% of the portfolio.

New Leaf Venture Partners withdrew a net $20.7M in Q3 2021, closing 1 position and reducing 1 holding. Its most notable exit was Chiasma, Inc. Common Stock, an estimated $5.37M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

Against the trend, New Leaf Venture Partners opened a new position in Rallybio worth $40.5M.

  • New Leaf Venture Partners's largest Q3 2021 buy was Rallybio: 287,700 shares worth $40.5M.
  • New Leaf Venture Partners's biggest Q3 2021 reduction was Arvinas, cutting an estimated $79.9M.
  • New Leaf Venture Partners fully exited Chiasma, Inc. Common Stock in Q3 2021, selling an estimated $5.37M.
  • New Leaf Venture Partners's ten largest holdings make up 89% of its $347M portfolio in Q3 2021.
  • New Leaf Venture Partners opened 4 new positions and closed 1 in Q3 2021.
  • New Leaf Venture Partners's portfolio value fell 11% quarter-over-quarter to $347M.

Based on New Leaf Venture Partners's 13F filing for Q3 2021, filed 12 Nov 2021.