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NLVP

New Leaf Venture Partners Portfolio holdings

AUM $43M
1-Year Est. Return 25.55%
This Fund
S&P 500
This Quarter Est. Return
+9.06%
1 Year Est. Return
-25.55%
3 Year Est. Return
+17.13%
5 Year Est. Return
+114.46%
10 Year Est. Return
+1,011.57%
AUM
$365M
AUM Growth
+$641K
Cap. Flow
+$17.3M
Cap. Flow %
4.74%
Top 10 Hldgs %
90.19%
Holding
24
New
4
Increased
–
Reduced
1
Closed
4

Top Buys

Rank Stock Value
1
HARP
Harpoon Therapeutics, Inc. Common Stock
HARP
+$38.4M
2
ALEC icon
Alector
ALEC
+$14.9M
3
CHMA
Chiasma, Inc. Common Stock
CHMA
+$1.76M

Top Sells

Rank Stock Value
1
WVE icon
Wave Life Sciences
WVE
+$17.9M
2
CRSP icon
CRISPR Therapeutics
CRSP
+$12.7M
3
AFMD
Affimed
AFMD
+$3.84M
4
TARA icon
Protara Therapeutics
TARA
+$3.46M
5
PDSB icon
PDS Biotechnology
PDSB
+$753K

Sector Composition

Rank Sector Weight
1 Healthcare 99.76%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DCPH
1
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$95.3M 26.1%
4,104,140
– –
PRNB
2
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$89.3M 24.46%
2,625,713
– –
ARVN icon
3
Arvinas
ARVN
$518M
$33.7M 9.23%
2,283,048
– –
HARP
4
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
$27.7M 7.58%
+292,141
New +$38.4M
STIM icon
5
Neuronetics
STIM
$120M
$23.5M 6.45%
1,543,115
– –
ALEC icon
6
Alector
ALEC
$164M
$14.7M 4.04%
+787,769
New +$14.9M
APTX
7
DELISTED
Aptinyx Inc. Common Stock
APTX
$13.3M 3.65%
3,290,079
– –
ITRM
8
DELISTED
Iterum Therapeutics
ITRM
$11.5M 3.16%
97,087
– –
OBSV
9
DELISTED
ObsEva SA Ordinary Shares
OBSV
$11.5M 3.16%
900,501
– –
SRRA
10
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$8.59M 2.35%
125,511
– –
COGT icon
11
Cogent Biosciences
COGT
$6.79B
$7.88M 2.16%
448,886
– –
ARAV
12
DELISTED
Aravive, Inc. Common Stock
ARAV
$6.83M 1.87%
970,659
– –
TECX
13
Tectonic Therapeutic
TECX
$573M
$4.75M 1.3%
17,963
– –
CRNX icon
14
Crinetics Pharmaceuticals
CRNX
$8.86B
$3.82M 1.05%
167,700
– –
NERV icon
15
Minerva Neurosciences
NERV
$188M
$3.33M 0.91%
52,913
– –
AFMD
16
DELISTED
Affimed
AFMD
$3.08M 0.84%
73,277
-106,723
-59% -$3.84M
CMRX
17
DELISTED
Chimerix, Inc.
CMRX
$2.83M 0.78%
1,350,000
– –
CHMA
18
DELISTED
Chiasma, Inc. Common Stock
CHMA
$2.08M 0.57%
+400,000
New +$1.76M
AVEO
19
DELISTED
AVEO Pharmaceuticals, Inc.
AVEO
$330K 0.09%
40,212
– –
CRSP icon
20
CRISPR Therapeutics
CRSP
$4.58B
– –
-444,708
Closed -$12.7M
PDSB icon
21
PDS Biotechnology
PDSB
$38.1M
– –
-117,243
Closed -$753K
TARA icon
22
Protara Therapeutics
TARA
$226M
– –
-38,080
Closed -$3.46M
WVE icon
23
Wave Life Sciences
WVE
$1.12B
– –
-425,429
Closed -$17.9M

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BAM
Broadcrest Asset Management Winter Park, Florida $44.1M AUM 4.51% 1-Year Est. Return
MAM
MPM Asset Management Boston, Massachusetts $44.5M AUM 47.28% 1-Year Est. Return
WCPI
Wynnchurch Capital Partners IV Rosemont, Illinois $44.8M AUM 11.91% 1-Year Est. Return
WAMC
Western Asset Management Company Pasadena, California $45.2M AUM 6.96% 1-Year Est. Return
CC
Corton Capital Carrying Place, Ontario, Canada $40.7M AUM 52.32% 1-Year Est. Return
CIEP
Constellation Investimentos e Participacoes Sao Paulo, Brazil $46.7M AUM 23.3% 1-Year Est. Return
IPI
Inflection Point Investments London, United Kingdom $46.9M AUM 18.35% 1-Year Est. Return
VSAM
Value Star Asset Management Hong Kong $49.2M AUM 60.1% 1-Year Est. Return

New Leaf Venture Partners's Q1 2019 Portfolio in Review

As of Q1 2019, New Leaf Venture Partners held 24 positions worth $365M, up 0.18% from $364M the previous quarter. Its ten largest holdings account for 90% of the portfolio.

New Leaf Venture Partners deployed $17.3M of net new capital in Q1 2019, opening 4 new positions. Its largest new stake was Harpoon Therapeutics, Inc. Common Stock: 292,141 shares worth $27.7M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, down from 100% a quarter earlier.

On the sell side, the largest reduction was Affimed, an estimated $3.84M trimmed.

  • New Leaf Venture Partners's largest Q1 2019 buy was Harpoon Therapeutics, Inc. Common Stock: 292,141 shares worth $27.7M.
  • New Leaf Venture Partners's biggest Q1 2019 reduction was Affimed, cutting an estimated $3.84M.
  • New Leaf Venture Partners fully exited Wave Life Sciences in Q1 2019, selling an estimated $17.9M.
  • New Leaf Venture Partners's ten largest holdings make up 90% of its $365M portfolio in Q1 2019.
  • New Leaf Venture Partners opened 4 new positions and closed 4 in Q1 2019.
  • New Leaf Venture Partners's portfolio value rose 0.18% quarter-over-quarter to $365M.

Based on New Leaf Venture Partners's 13F filing for Q1 2019, filed 15 May 2019.