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NLVP

New Leaf Venture Partners Portfolio holdings

AUM $43M
1-Year Est. Return 25.55%
This Fund
S&P 500
This Quarter Est. Return
+9.98%
1 Year Est. Return
-25.55%
3 Year Est. Return
+17.13%
5 Year Est. Return
+114.46%
10 Year Est. Return
+1,011.57%
AUM
$331M
AUM Growth
-$42.5M
Cap. Flow
-$57.1M
Cap. Flow %
-17.29%
Top 10 Hldgs %
92.31%
Holding
21
New
–
Increased
2
Reduced
5
Closed
2

Top Buys

Rank Stock Value
1
CHMA
Chiasma, Inc. Common Stock
CHMA
+$1.9M
2
TECX
Tectonic Therapeutic
TECX
+$1.89M

Top Sells

Rank Stock Value
1
DCPH
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
+$30.5M
2
PRNB
Principia Biopharma Inc. Common Stock
PRNB
+$23.1M
3
ALEC icon
Alector
ALEC
+$2.68M
4
AFMD
Affimed
AFMD
+$2.1M
5
STIM icon
Neuronetics
STIM
+$1.83M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DCPH
1
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$104M 31.57%
3,074,825
-1,029,315
-25% -$30.5M
PRNB
2
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$56.4M 17.05%
1,996,588
-629,125
-24% -$23.1M
ARVN icon
3
Arvinas
ARVN
$523M
$49.2M 14.88%
2,283,048
– –
HARP
4
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
$39.9M 12.07%
292,141
– –
APTX
5
DELISTED
Aptinyx Inc. Common Stock
APTX
$11.5M 3.47%
3,290,079
– –
STIM icon
6
Neuronetics
STIM
$125M
$11.4M 3.46%
1,376,006
-167,109
-11% -$1.83M
ALEC icon
7
Alector
ALEC
$167M
$9.22M 2.79%
639,569
-148,200
-19% -$2.68M
ITRM
8
DELISTED
Iterum Therapeutics
ITRM
$8.4M 2.54%
97,087
– –
OBSV
9
DELISTED
ObsEva SA Ordinary Shares
OBSV
$7.5M 2.27%
900,501
– –
ARAV
10
DELISTED
Aravive, Inc. Common Stock
ARAV
$7.28M 2.2%
970,659
– –
TECX
11
Tectonic Therapeutic
TECX
$579M
$4.46M 1.35%
26,296
+8,333
+46% +$1.89M
CHMA
12
DELISTED
Chiasma, Inc. Common Stock
CHMA
$3.64M 1.1%
735,700
+335,700
+84% +$1.9M
XFOR icon
13
X4 Pharmaceuticals
XFOR
$366M
$3.62M 1.1%
9,500
– –
NERV icon
14
Minerva Neurosciences
NERV
$197M
$3.48M 1.05%
56,188
– –
CMRX
15
DELISTED
Chimerix, Inc.
CMRX
$3.17M 0.96%
1,350,000
– –
COGT icon
16
Cogent Biosciences
COGT
$6.82B
$2.59M 0.78%
448,886
– –
CRNX icon
17
Crinetics Pharmaceuticals
CRNX
$8.86B
$2.12M 0.64%
141,000
-26,700
-16% -$519K
SRRA
18
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$1.96M 0.59%
125,511
– –
PDSB icon
19
PDS Biotechnology
PDSB
$39M
$396K 0.12%
117,242
– –
AFMD
20
DELISTED
Affimed
AFMD
– –
-73,277
Closed -$2.1M
AVEO
21
DELISTED
AVEO Pharmaceuticals, Inc.
AVEO
– –
-40,212
Closed -$271K

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New Leaf Venture Partners's Q3 2019 Portfolio in Review

As of Q3 2019, New Leaf Venture Partners held 21 positions worth $331M, down 11% from $373M the previous quarter. Its ten largest holdings account for 92% of the portfolio.

New Leaf Venture Partners withdrew a net $57.1M in Q3 2019, closing 2 positions and reducing 5 holdings. Its most notable exit was Affimed, an estimated $2.1M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

Against the trend, New Leaf Venture Partners added an estimated $1.9M to Chiasma, Inc. Common Stock.

  • New Leaf Venture Partners added most to Chiasma, Inc. Common Stock in Q3 2019, an estimated $1.9M increase.
  • New Leaf Venture Partners's biggest Q3 2019 reduction was Deciphera Pharmaceuticals, Inc. Common Stock, cutting an estimated $30.5M.
  • New Leaf Venture Partners fully exited Affimed in Q3 2019, selling an estimated $2.1M.
  • New Leaf Venture Partners's ten largest holdings make up 92% of its $331M portfolio in Q3 2019.
  • New Leaf Venture Partners opened 0 new positions and closed 2 in Q3 2019.
  • New Leaf Venture Partners's portfolio value fell 11% quarter-over-quarter to $331M.

Based on New Leaf Venture Partners's 13F filing for Q3 2019, filed 14 Nov 2019.