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NLVP

New Leaf Venture Partners Portfolio holdings

AUM $43M
1-Year Est. Return 25.55%
This Fund
S&P 500
This Quarter Est. Return
-14.38%
1 Year Est. Return
-25.55%
3 Year Est. Return
+17.13%
5 Year Est. Return
+114.46%
10 Year Est. Return
+1,011.57%
AUM
$138M
AUM Growth
-$30.4M
Cap. Flow
+$1.44M
Cap. Flow %
1.05%
Top 10 Hldgs %
93.65%
Holding
20
New
1
Increased
1
Reduced
1
Closed
3

Top Buys

Rank Stock Value
1
RLYB icon
Rallybio
RLYB
+$7.38M
2
RCKT icon
Rocket Pharmaceuticals
RCKT
+$2.18M

Top Sells

Rank Stock Value
1
DICE
DICE Therapeutics, Inc. Common Stock
DICE
+$6.03M
2
RCOR
Renovacor, Inc.
RCOR
+$1.69M
3
PDSB icon
PDS Biotechnology
PDSB
+$348K
4
ADXN
Addex Therapeutics
ADXN
+$40K

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARVN icon
1
Arvinas
ARVN
$572M
$44.1M 31.94%
1,289,521
– –
RLYB icon
2
Rallybio
RLYB
$85.8M
$21.7M 15.7%
412,700
+125,000
+43% +$7.38M
DCPH
3
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$19.8M 14.35%
1,209,571
– –
EWTX icon
4
Edgewise Therapeutics
EWTX
$4.68B
$13.9M 10.06%
1,553,661
– –
DICE
5
DELISTED
DICE Therapeutics, Inc. Common Stock
DICE
$11.6M 8.4%
371,693
-185,000
-33% -$6.03M
COGT icon
6
Cogent Biosciences
COGT
$7.24B
$5.8M 4.2%
501,530
– –
PASG icon
7
Passage Bio
PASG
$14.1M
$3.45M 2.5%
124,896
– –
AMYT
8
DELISTED
Amryt Pharma plc American Depositary Shares
AMYT
$3.28M 2.38%
449,737
– –
ALEC icon
9
Alector
ALEC
$198M
$3.13M 2.27%
339,569
– –
CRNX icon
10
Crinetics Pharmaceuticals
CRNX
$8.92B
$2.58M 1.87%
141,000
– –
RCKT icon
11
Rocket Pharmaceuticals
RCKT
$394M
$2.31M 1.68%
+118,242
New +$2.18M
HARP
12
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
$2.29M 1.66%
315,670
– –
CMRX
13
DELISTED
Chimerix, Inc.
CMRX
$2.28M 1.65%
1,224,600
– –
ARAV
14
DELISTED
Aravive, Inc. Common Stock
ARAV
$1.25M 0.9%
946,423
– –
XFOR icon
15
X4 Pharmaceuticals
XFOR
$438M
$333K 0.24%
11,167
– –
TECX
16
Tectonic Therapeutic
TECX
$585M
$225K 0.16%
26,296
– –
ITRM
17
DELISTED
Iterum Therapeutics
ITRM
$81.6K 0.06%
97,084
– –
ADXN
18
Addex Therapeutics
ADXN
$7.34M
– –
-2,500
Closed -$40K
PDSB icon
19
PDS Biotechnology
PDSB
$43.4M
– –
-117,242
Closed -$348K
RCOR
20
DELISTED
Renovacor, Inc.
RCOR
– –
-670,689
Closed -$1.69M

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WCPI
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WAMC
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New Leaf Venture Partners's Q4 2022 Portfolio in Review

As of Q4 2022, New Leaf Venture Partners held 20 positions worth $138M, down 18% from $169M the previous quarter. Its ten largest holdings account for 94% of the portfolio.

New Leaf Venture Partners's Q4 2022 filing shows 1 new, 1 increased, 1 reduced and 3 closed positions. Its largest new stake was Rocket Pharmaceuticals: 118,242 shares worth $2.31M. The largest sale was DICE Therapeutics, Inc. Common Stock, an estimated $6.03M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • New Leaf Venture Partners's largest Q4 2022 buy was Rocket Pharmaceuticals: 118,242 shares worth $2.31M.
  • New Leaf Venture Partners added most to Rallybio in Q4 2022, an estimated $7.38M increase.
  • New Leaf Venture Partners's biggest Q4 2022 reduction was DICE Therapeutics, Inc. Common Stock, cutting an estimated $6.03M.
  • New Leaf Venture Partners fully exited Renovacor, Inc. in Q4 2022, selling an estimated $1.69M.
  • New Leaf Venture Partners's ten largest holdings make up 94% of its $138M portfolio in Q4 2022.
  • New Leaf Venture Partners opened 1 new position and closed 3 in Q4 2022.
  • New Leaf Venture Partners's portfolio value fell 18% quarter-over-quarter to $138M.

Based on New Leaf Venture Partners's 13F filing for Q4 2022, filed 6 Feb 2023.