New Leaf Venture Partners’s Aptinyx Inc. Common Stock APTX Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2022 Q3	–	Sell	-3,290,079	Closed	-$1.84M	–	20
2022 Q2	$1.84M	Hold	3,290,079	–	–	1.19%	14
2022 Q1	$7.47M	Hold	3,290,079	–	–	3.68%	8
2021 Q4	$8.79M	Hold	3,290,079	–	–	3.18%	9
2021 Q3	$7.7M	Hold	3,290,079	–	–	2.22%	10
2021 Q2	$9.31M	Hold	3,290,079	–	–	2.39%	7
2021 Q1	$9.87M	Hold	3,290,079	–	–	2.3%	7
2020 Q4	$11.4M	Hold	3,290,079	–	–	2.63%	5
2020 Q3	$11.1M	Hold	3,290,079	–	–	4.48%	5
2020 Q2	$13.7M	Hold	3,290,079	–	–	3.94%	6
2020 Q1	$7.11M	Hold	3,290,079	–	–	2.13%	7
2019 Q4	$11.3M	Hold	3,290,079	–	–	2.44%	7
2019 Q3	$11.5M	Hold	3,290,079	–	–	3.47%	5
2019 Q2	$11M	Hold	3,290,079	–	–	2.95%	7
2019 Q1	$13.3M	Hold	3,290,079	–	–	3.65%	7
2018 Q4	$54.4M	Hold	3,290,079	–	–	14.94%	3
2018 Q3	$95.3M	Hold	3,290,079	–	–	17.34%	2
2018 Q2	$79.5M	Buy	+3,290,079	New	+$70.4M	19.19%	2