MIM
UPB

MetLife Investment Management’s Upstream Bio Inc UPB Stock Holding History

MetLife Investment Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$174K Sell
19,380
-298
-2% -$5.36K ﹤0.01% 2298
2025
Q4 		$534K Sell
19,678
-2,013
-9% -$50.1K ﹤0.01% 1764
2025
Q3 		$408K Hold
21,691
– – ﹤0.01% 1904
2025
Q2 		$238K Buy
21,691
+10,657
+97% +$98.4K ﹤0.01% 2098
2025
Q1 		$67.5K Hold
11,034
– – ﹤0.01% 2657
2024
Q4 		$181K Buy
+11,034
New +$246K ﹤0.01% 2349

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

MetLife Investment Management's UPB Position: Q1 2026 in Review

MetLife Investment Management reduced its Upstream Bio Inc (UPB) stake by 1.5% in Q1 2026, selling an estimated $5.36K and leaving 19,380 shares worth $174K. The position accounts for ﹤0.01% of the portfolio, ranked #2298.

MetLife Investment Management first reported a position in UPB in Q4 2024 and has held it in 6 quarters since. The position peaked at $534K in Q4 2025. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • MetLife Investment Management held 19,380 shares of Upstream Bio Inc worth $174K as of Q1 2026.
  • MetLife Investment Management sold 298 Upstream Bio Inc shares in Q1 2026, an estimated $5.36K.
  • Upstream Bio Inc made up ﹤0.01% of MetLife Investment Management's portfolio in Q1 2026, its #2298 holding.
  • MetLife Investment Management first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 6 quarters since.
  • MetLife Investment Management's Upstream Bio Inc position peaked at $534K in Q4 2025.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on MetLife Investment Management's 13F filing for Q1 2026, filed 14 May 2026.