Jim Simons’s Ionis Pharmaceuticals IONS Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$22.9M Buy
305,549
+81,942
+37% +$6.47M 0.04% 594
2025
Q4
$17.7M Sell
223,607
-263,107
-54% -$19.8M 0.03% 655
2025
Q3
$31.8M Buy
486,714
+216,000
+80% +$10.5M 0.04% 521
2025
Q2
$10.7M Buy
270,714
+117,200
+76% +$3.84M 0.01% 1023
2025
Q1
$4.63M Sell
153,514
-52,000
-25% -$1.7M 0.01% 1481
2024
Q4
$7.18M Buy
205,514
+15,000
+8% +$561K 0.01% 1216
2024
Q3
$7.63M Sell
190,514
-59,000
-24% -$2.75M 0.01% 1186
2024
Q2
$11.9M Buy
249,514
+69,800
+39% +$2.86M 0.02% 824
2024
Q1
$7.79M Buy
179,714
+67,300
+60% +$3.21M 0.01% 1136
2023
Q4
$5.69M Sell
112,414
-157,386
-58% -$7.54M 0.01% 1272
2023
Q3
$12.2M Sell
269,800
-100,700
-27% -$4.15M 0.02% 800
2023
Q2
$15.2M Sell
370,500
-265,814
-42% -$10.2M 0.02% 809
2023
Q1
$22.7M Sell
636,314
-542,500
-46% -$20.4M 0.03% 648
2022
Q4
$44.5M Buy
1,178,814
+311,100
+36% +$13.1M 0.06% 374
2022
Q3
$38.4M Buy
867,714
+252,900
+41% +$10.7M 0.05% 408
2022
Q2
$22.8M Buy
614,814
+479,900
+356% +$18.1M 0.03% 662
2022
Q1
$5M Sell
134,914
-95,900
-42% -$3.14M 0.01% 1596
2021
Q4
$7.02M Buy
230,814
+133,100
+136% +$4.19M 0.01% 1287
2021
Q3
$3.28M Sell
97,714
-678,700
-87% -$25.6M ﹤0.01% 1718
2021
Q2
$31M Buy
776,414
+189,000
+32% +$7.4M 0.04% 516
2021
Q1
$26.4M Sell
587,414
-157,934
-21% -$8.81M 0.03% 626
2020
Q4
$42.1M Sell
745,348
-721,819
-49% -$36M 0.05% 410
2020
Q3
$69.6M Sell
1,467,167
-285,700
-16% -$15.9M 0.07% 294
2020
Q2
$103M Buy
1,752,867
+64,456
+4% +$3.59M 0.09% 231
2020
Q1
$79.8M Sell
1,688,411
-350,300
-17% -$19.5M 0.08% 266
2019
Q4
$123M Buy
2,038,711
+225,700
+12% +$13.4M 0.09% 225
2019
Q3
$109M Buy
1,813,011
+57,700
+3% +$3.76M 0.09% 252
2019
Q2
$113M Buy
+1,755,311
New +$124M 0.1% 233
2018
Q3
Sell
-109,914
Closed -$4.58M 3434
2018
Q2
$4.58M Sell
109,914
-117,800
-52% -$5.22M 0.01% 1836
2018
Q1
$10M Buy
+227,714
New +$11.6M 0.01% 1369
2017
Q3
Sell
-82,414
Closed -$4.19M 3267
2017
Q2
$4.19M Sell
82,414
-230,800
-74% -$10.7M 0.01% 1822
2017
Q1
$12.6M Sell
313,214
-136,300
-30% -$6.12M 0.02% 1091
2016
Q4
$21.5M Buy
449,514
+174,700
+64% +$6.91M 0.03% 737
2016
Q3
$10.1M Buy
274,814
+91,714
+50% +$2.87M 0.02% 1145
2016
Q2
$4.26M Buy
183,100
+123,700
+208% +$3.99M 0.01% 1702
2016
Q1
$2.41M Sell
59,400
-75,914
-56% -$3.08M ﹤0.01% 2102
2015
Q4
$8.38M Sell
135,314
-341,500
-72% -$18.4M 0.02% 1114
2015
Q3
$19.3M Buy
476,814
+425,500
+829% +$22M 0.05% 514
2015
Q2
$2.95M Buy
+51,314
New +$3.26M 0.01% 1799
2014
Q2
Sell
-136,914
Closed -$5.92M 2863
2014
Q1
$5.92M Sell
136,914
-189,200
-58% -$9.17M 0.01% 1164
2013
Q4
$13M Sell
326,114
-2,800
-0.9% -$99.8K 0.03% 664
2013
Q3
$12.3M Buy
328,914
+301,000
+1,078% +$8.99M 0.03% 694
2013
Q2
$750K Buy
+27,914
New +$594K ﹤0.01% 2061

Other funds holding IONS

Jim Simons's IONS Position: Q1 2026 in Review

Jim Simons increased its Ionis Pharmaceuticals (IONS) stake by 37% in Q1 2026, buying an estimated $6.47M and bringing the position to 305,549 shares worth $22.9M. The position accounts for 0.04% of the portfolio, ranked #594.

Jim Simons first reported a position in IONS in Q2 2013 and has held it in 43 quarters since. The position peaked at $123M in Q4 2019. 494 funds tracked by Wall St. Rank hold IONS as of Q1 2026.

  • Jim Simons held 305,549 shares of Ionis Pharmaceuticals worth $22.9M as of Q1 2026.
  • Jim Simons bought 81,942 Ionis Pharmaceuticals shares in Q1 2026, an estimated $6.47M.
  • Ionis Pharmaceuticals made up 0.04% of Jim Simons's portfolio in Q1 2026, its #594 holding.
  • Jim Simons first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 43 quarters since.
  • Jim Simons's Ionis Pharmaceuticals position peaked at $123M in Q4 2019.
  • 494 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.