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Jefferies Financial Group’s Praxis Precision Medicines PRAX Stock Holding History

Jefferies Financial Group’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-27,000
Closed -$1.43M – 2026
2025
Q3 		$1.43M Hold
27,000
– – 0.01% 755
2025
Q2 		$1.14M Buy
+27,000
New +$1.03M 0.01% 696

Other funds holding PRAX

Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

Jefferies Financial Group's PRAX Position: Q4 2025 in Review

Jefferies Financial Group sold out of Praxis Precision Medicines (PRAX) in Q4 2025, closing a stake of 2,000 shares — an estimated $106K sold.

Jefferies Financial Group first reported a position in PRAX in Q2 2025 and held it in 2 quarters. The position peaked at $210K in Q2 2025. 250 funds tracked by Wall St. Rank hold PRAX as of Q4 2025.

  • Jefferies Financial Group reported no remaining Praxis Precision Medicines position as of Q4 2025 after selling out during the quarter.
  • Jefferies Financial Group sold 2,000 Praxis Precision Medicines shares in Q4 2025, an estimated $106K.
  • Jefferies Financial Group first reported a position in Praxis Precision Medicines in Q2 2025 and held it in 2 quarters.
  • Jefferies Financial Group's Praxis Precision Medicines position peaked at $210K in Q2 2025.
  • 250 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q4 2025.

Based on Jefferies Financial Group's 13F filing for Q4 2025, filed 9 Feb 2026.