Jane Street’s Ionis Pharmaceuticals IONS Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$21.7M Buy
288,700
+272,800
+1,716% +$21.5M ﹤0.01% 1714
2025
Q4
$1.26M Sell
15,900
-11,300
-42% -$851K ﹤0.01% 5679
2025
Q3
$1.78M Buy
27,200
+4,100
+18% +$200K ﹤0.01% 5157
2025
Q2
$913K Buy
23,100
+7,000
+43% +$229K ﹤0.01% 5783
2025
Q1
$486K Sell
16,100
-13,300
-45% -$436K ﹤0.01% 6918
2024
Q4
$1.03M Sell
29,400
-300
-1% -$11.2K ﹤0.01% 5340
2024
Q3
$1.19M Sell
29,700
-31,600
-52% -$1.47M ﹤0.01% 5542
2024
Q2
$2.92M Buy
61,300
+27,600
+82% +$1.13M ﹤0.01% 3854
2024
Q1
$1.46M Buy
33,700
+11,200
+50% +$534K ﹤0.01% 4695
2023
Q4
$1.14M Sell
22,500
-17,300
-43% -$829K ﹤0.01% 5333
2023
Q3
$1.81M Buy
39,800
+22,500
+130% +$928K ﹤0.01% 4225
2023
Q2
$710K Buy
17,300
+3,200
+23% +$123K ﹤0.01% 5770
2023
Q1
$504K Sell
14,100
-28,600
-67% -$1.07M ﹤0.01% 6304
2022
Q4
$1.61M Sell
42,700
-48,300
-53% -$2.03M ﹤0.01% 4195
2022
Q3
$4.03M Buy
91,000
+26,100
+40% +$1.1M ﹤0.01% 2963
2022
Q2
$2.4M Buy
64,900
+18,400
+40% +$694K ﹤0.01% 3825
2022
Q1
$1.72M Sell
46,500
-19,100
-29% -$625K ﹤0.01% 5043
2021
Q4
$2M Buy
65,600
+31,900
+95% +$1M ﹤0.01% 4498
2021
Q3
$1.13M Buy
33,700
+7,800
+30% +$294K ﹤0.01% 5671
2021
Q2
$1.03M Sell
25,900
-10,100
-28% -$396K ﹤0.01% 5766
2021
Q1
$1.62M Sell
36,000
-8,900
-20% -$496K ﹤0.01% 4433
2020
Q4
$2.54M Hold
44,900
﹤0.01% 3103
2020
Q3
$2.13M Sell
44,900
-6,400
-12% -$356K ﹤0.01% 2932
2020
Q2
$3.02M Buy
51,300
+13,200
+35% +$734K ﹤0.01% 2493
2020
Q1
$1.8M Buy
+38,100
New +$2.12M ﹤0.01% 2130
2017
Q4
Sell
-4,900
Closed -$248K 4864
2017
Q3
$248K Buy
+4,900
New +$257K ﹤0.01% 3905
2017
Q1
Sell
-14,600
Closed -$698K 4403
2016
Q4
$698K Sell
14,600
-1,600
-10% -$63.3K ﹤0.01% 2483
2016
Q3
$594K Sell
16,200
-144,600
-90% -$4.52M ﹤0.01% 2578
2016
Q2
$3.75M Buy
160,800
+149,400
+1,311% +$4.82M 0.02% 786
2016
Q1
$462K Buy
11,400
+4,100
+56% +$167K ﹤0.01% 2694
2015
Q4
$452K Buy
+7,300
New +$394K ﹤0.01% 2603
2015
Q3
Sell
-12,000
Closed -$691K 3853
2015
Q2
$691K Sell
12,000
-2,800
-19% -$178K ﹤0.01% 1953
2015
Q1
$942K Buy
+14,800
New +$1M 0.01% 1424

Other funds holding IONS

Jane Street's IONS Position: Q1 2026 in Review

Jane Street increased its Ionis Pharmaceuticals (IONS) stake by 530% in Q1 2026, buying an estimated $12.7M and bringing the position to 191,818 shares worth $14.4M. The position accounts for ﹤0.01% of the portfolio, ranked #2111.

Jane Street first reported a position in IONS in Q2 2013 and has held it in 47 quarters since. The position peaked at $23.9M in Q3 2025. 494 funds tracked by Wall St. Rank hold IONS as of Q1 2026.

  • Jane Street held 191,818 shares of Ionis Pharmaceuticals worth $14.4M as of Q1 2026.
  • Jane Street bought 161,347 Ionis Pharmaceuticals shares in Q1 2026, an estimated $12.7M.
  • Ionis Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #2111 holding.
  • Jane Street first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 47 quarters since.
  • Jane Street's Ionis Pharmaceuticals position peaked at $23.9M in Q3 2025.
  • 494 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.