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Ghost Tree Capital Portfolio holdings

AUM $331M Turnover 44%
1-Year Est. Return 70.11%
This Fund
S&P 500
This Quarter Est. Return
+14.65%
1 Year Est. Return
+70.11%
3 Year Est. Return
+265.05%
5 Year Est. Return
+3,034.98%
10 Year Est. Return
+22,104.75%
AUM
$331M
AUM Growth
+$11.7M
Cap. Flow
-$38.1M
Cap. Flow %
-11.51%
Top 10 Hldgs %
42.42%
Holding
75
New
12
Increased
16
Reduced
23
Closed
21
Avg Time Held Equity + Options
0.7 years
Top 10 Avg Time Held Equity + Options
0.2 years
Top 20 Avg Time Held Equity + Options
0.4 years
Avg Time Held Equity only
0.8 years
Top 10 Avg Time Held Equity only
0.2 years
Top 20 Avg Time Held Equity only
0.8 years

Sector Composition

Rank Sector Weight
1 Healthcare 83.31%
2 Miscellaneous 16.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
ATYR icon
51
aTyr Pharma
ATYR
$16.8M
$1.41M 0.43%
800,000
– –
2024 Q1
2 quarters
LRMR icon
52
Larimar Therapeutics
LRMR
$220M
$1.31M 0.4%
+200,000
New +$1.61M
2024 Q3
0 quarters
ENGN icon
53
enGene Therapeutics
ENGN
$106M
$1.06M 0.32%
160,898
-259,433
-62% -$1.93M
2024 Q1
2 quarters
AMLX icon
54
Amylyx Pharmaceuticals
AMLX
$3.43B
$1.05M 0.32%
+325,000
New +$731K
2024 Q3
0 quarters
ACAD icon
55
Acadia Pharmaceuticals
ACAD
$3.41B
– –
-225,000
Closed -$3.66M –
ALNY icon
56
Alnylam Pharmaceuticals
ALNY
$31.2B
– –
-22,500
Closed -$5.47M –
ALNY icon
57
PUT
Alnylam Pharmaceuticals
ALNY
$31.2B
– –
-68,400
Closed -$16.6M –
ANNX icon
58
CALL
Annexon
ANNX
$760M
– –
-214,500
Closed -$1.05M –
ANTX icon
59
AN2 Therapeutics
ANTX
$127M
– –
-219,331
Closed -$472K –
ARWR icon
60
Arrowhead Research
ARWR
$8.08B
– –
-35,000
Closed -$910K –
BHVN icon
61
Biohaven
BHVN
$1.71B
– –
-490,000
Closed -$19.1M –
CABA icon
62
Cabaletta Bio
CABA
$251M
– –
-370,899
Closed -$2.77M –
CTMX icon
63
CytomX Therapeutics
CTMX
$510M
– –
-300,000
Closed -$366K –
CYTK icon
64
Cytokinetics
CYTK
$8.71B
– –
-33,200
Closed -$1.8M –
ELEV icon
65
DELISTED
Elevation Oncology
ELEV
– –
-600,000
Closed -$1.62M –
KRYS icon
66
Krystal Biotech
KRYS
$9.48B
– –
-8,500
Closed -$1.56M –
MGNX icon
67
MacroGenics
MGNX
$212M
– –
-150,000
Closed -$638K –
NTLA icon
68
Intellia Therapeutics
NTLA
$1.62B
– –
-25,000
Closed -$560K –
PMVP icon
69
PMV Pharmaceuticals
PMVP
$67.1M
– –
-375,000
Closed -$608K –
PTCT icon
70
PTC Therapeutics
PTCT
$5.14B
– –
-19,000
Closed -$581K –
RAPT icon
71
CALL
DELISTED
RAPT Therapeutics
RAPT
– –
-37,500
Closed -$915K –
SGMT icon
72
Sagimet Biosciences
SGMT
$628M
– –
-225,000
Closed -$770K –
WVE icon
73
Wave Life Sciences
WVE
$625M
– –
-200,000
Closed -$998K –
ITCI icon
74
DELISTED
Intra-Cellular Therapies Inc.
ITCI
– –
-10,000
Closed -$685K –
RVNC icon
75
DELISTED
Revance Therapeutics, Inc.
RVNC
– –
-225,000
Closed -$578K –

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Ghost Tree Capital's Q3 2024 Portfolio in Review

As of Q3 2024, Ghost Tree Capital held 75 positions worth $331M, up 3.7% from $319M the previous quarter. Its ten largest holdings account for 42% of the portfolio.

Ghost Tree Capital withdrew a net $38.1M in Q3 2024, closing 21 positions and reducing 23 holdings. Its most notable exit was Biohaven, an estimated $19.1M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 83% of assets, down from 90% a quarter earlier, followed by Miscellaneous.

Against the trend, Ghost Tree Capital opened a new position in Novo Nordisk worth $13.1M.

  • Ghost Tree Capital's largest Q3 2024 buy was Novo Nordisk: 110,000 shares worth $13.1M.
  • Ghost Tree Capital added most to Blueprint Medicines in Q3 2024, an estimated $9.9M increase.
  • Ghost Tree Capital's biggest Q3 2024 reduction was Viridian Therapeutics, cutting an estimated $8.38M.
  • Ghost Tree Capital fully exited Biohaven in Q3 2024, selling an estimated $19.1M.
  • Ghost Tree Capital's ten largest holdings make up 42% of its $331M portfolio in Q3 2024.
  • Ghost Tree Capital opened 12 new positions and closed 21 in Q3 2024.
  • Ghost Tree Capital's portfolio value rose 3.7% quarter-over-quarter to $331M.

Based on Ghost Tree Capital's 13F filing for Q3 2024, filed 14 Nov 2024.