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Ghost Tree Capital Portfolio holdings

AUM $331M Turnover 44%
1-Year Est. Return 70.11%
This Fund
S&P 500
This Quarter Est. Return
+23.2%
1 Year Est. Return
+70.11%
3 Year Est. Return
+265.05%
5 Year Est. Return
+3,034.98%
10 Year Est. Return
+22,104.75%
AUM
$426M
AUM Growth
-$44.5M
Cap. Flow
-$69.2M
Cap. Flow %
-16.23%
Top 10 Hldgs %
50.35%
Holding
88
New
25
Increased
8
Reduced
14
Closed
39
Avg Time Held Equity + Options
0.4 years
Top 10 Avg Time Held Equity + Options
0.2 years
Top 20 Avg Time Held Equity + Options
0.3 years
Avg Time Held Equity only
0.3 years
Top 10 Avg Time Held Equity only
0.1 years
Top 20 Avg Time Held Equity only
0.2 years

Sector Composition

Rank Sector Weight
1 Healthcare 67.49%
2 Miscellaneous 32.51%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
XBI icon
1
PUT
State Street SPDR S&P Biotech ETF
XBI
$10.2B
$72.1M 16.92%
850,000
+500,000
+143% +$41.9M
2016 Q1
7 quarters
IMMU
2
DELISTED
Immunomedics Inc
IMMU
$24.9M 5.83%
1,538,000
-408,946
-21% -$4.83M
2016 Q2
6 quarters
IMMU
3
CALL
DELISTED
Immunomedics Inc
IMMU
$21M 4.93%
+1,300,000
New +$15.3M
2017 Q4
0 quarters
ARGX icon
4
argenx
ARGX
$61.7B
$15.8M 3.7%
250,000
-2,534
-1% -$83K
2017 Q2
2 quarters
CELG
5
CALL
DELISTED
Celgene Corp
CELG
$15.7M 3.67%
+150,000
New +$16.9M
2017 Q4
0 quarters
ESPR icon
6
DELISTED
Esperion Therapeutics
ESPR
$15.1M 3.55%
+230,000
New +$12.4M
2017 Q4
0 quarters
ALXN
7
DELISTED
Alexion Pharmaceuticals
ALXN
$13.8M 3.23%
115,000
+15,000
+15% +$1.83M
2017 Q2
2 quarters
GBT
8
DELISTED
Global Blood Therapeutics, Inc.
GBT
$12.8M 3%
325,000
+75,000
+30% +$2.8M
2017 Q3
1 quarter
AGN
9
CALL
DELISTED
Allergan plc
AGN
$12.3M 2.88%
+75,000
New +$13.5M
2017 Q4
0 quarters
BPMC icon
10
DELISTED
Blueprint Medicines
BPMC
$11.3M 2.65%
+150,000
New +$10.6M
2017 Q4
0 quarters
PTLA
11
DELISTED
Portola Pharmaceuticals, Inc.
PTLA
$11M 2.57%
+225,000
New +$11.4M
2017 Q4
0 quarters
MRTX
12
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$11M 2.57%
+600,000
New +$9.31M
2017 Q4
0 quarters
VTRS icon
13
Viatris
VTRS
$23.7B
$10.6M 2.48%
+250,000
New +$9.6M
2017 Q4
0 quarters
ASND icon
14
Ascendis Pharma A/S
ASND
$17.5B
$10M 2.35%
250,000
+50,000
+25% +$1.82M
2017 Q3
1 quarter
AVXS
15
DELISTED
AveXis, Inc. Common Stock
AVXS
$9.41M 2.21%
85,000
-19,539
-19% -$1.96M
2016 Q3
5 quarters
BMY icon
16
CALL
Bristol-Myers Squibb
BMY
$127B
$9.19M 2.16%
150,000
– –
2016 Q3
5 quarters
XLRN
17
DELISTED
Acceleron Pharma
XLRN
$8.49M 1.99%
200,000
-150,000
-43% -$5.63M
2016 Q4
4 quarters
VRAY
18
DELISTED
ViewRay, Inc.
VRAY
$8.33M 1.95%
900,000
+200,000
+29% +$1.6M
2017 Q2
2 quarters
DBVT icon
19
DBV Technologies S.A. American Depositary Shares
DBVT
$718M
$8M 1.87%
32,500
-9,589
-23% -$2.77M
2016 Q3
5 quarters
AGN
20
DELISTED
Allergan plc
AGN
$7.48M 1.76%
+45,750
New +$8.21M
2017 Q4
0 quarters
ZGNX
21
DELISTED
Zogenix, Inc.
ZGNX
$7.21M 1.69%
180,000
-420,000
-70% -$16.1M
2016 Q3
5 quarters
SAGE icon
22
PUT
DELISTED
Sage Therapeutics
SAGE
$7.2M 1.69%
43,700
-106,300
-71% -$10.3M
2017 Q3
1 quarter
JUNO
23
DELISTED
Juno Therapeutics, Inc.
JUNO
$6.86M 1.61%
150,000
+50,000
+50% +$2.49M
2017 Q2
2 quarters
CLVS
24
DELISTED
Clovis Oncology, Inc.
CLVS
$6.8M 1.59%
+100,000
New +$6.99M
2017 Q4
0 quarters
LJPC
25
DELISTED
La Jolla Pharmaceutical Company
LJPC
$6.44M 1.51%
+200,000
New +$6.54M
2017 Q4
0 quarters

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Ghost Tree Capital's Q4 2017 Portfolio in Review

As of Q4 2017, Ghost Tree Capital held 88 positions worth $426M, down 9.4% from $471M the previous quarter. Its ten largest holdings account for 50% of the portfolio.

Ghost Tree Capital withdrew a net $69.2M in Q4 2017, closing 39 positions and reducing 14 holdings. Its most notable exit was Neurocrine Biosciences, an estimated $13.8M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 67% of assets, down from 71% a quarter earlier, followed by Miscellaneous.

Against the trend, Ghost Tree Capital opened a new position in Esperion Therapeutics worth $15.1M.

  • Ghost Tree Capital's largest Q4 2017 buy was Esperion Therapeutics: 230,000 shares worth $15.1M.
  • Ghost Tree Capital added most to Global Blood Therapeutics, Inc. in Q4 2017, an estimated $2.8M increase.
  • Ghost Tree Capital's biggest Q4 2017 reduction was Zogenix, Inc., cutting an estimated $16.1M.
  • Ghost Tree Capital fully exited Neurocrine Biosciences in Q4 2017, selling an estimated $13.8M.
  • Ghost Tree Capital's ten largest holdings make up 50% of its $426M portfolio in Q4 2017.
  • Ghost Tree Capital opened 25 new positions and closed 39 in Q4 2017.
  • Ghost Tree Capital's portfolio value fell 9.4% quarter-over-quarter to $426M.

Based on Ghost Tree Capital's 13F filing for Q4 2017, filed 14 Feb 2018.