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Ghost Tree Capital Portfolio holdings

AUM $331M
1-Year Est. Return 70.11%
This Fund
S&P 500
This Quarter Est. Return
+1.9%
1 Year Est. Return
+70.11%
3 Year Est. Return
+265.05%
5 Year Est. Return
+3,034.98%
10 Year Est. Return
+22,104.75%
AUM
$364M
AUM Growth
-$61.7M
Cap. Flow
-$51.8M
Cap. Flow %
-14.24%
Top 10 Hldgs %
49.17%
Holding
67
New
17
Increased
9
Reduced
10
Closed
14
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
XBI icon
1
CALL
State Street SPDR S&P Biotech ETF
XBI
$10.4B
$40.6M 11.17%
+300,000
New +$39.4M
RAPT
2
DELISTED
RAPT Therapeutics
RAPT
$18.1M 4.98%
+71,250
New +$13.3M
ASND icon
3
Ascendis Pharma A/S
ASND
$17.1B
$17.8M 4.88%
135,000
FATE icon
4
Fate Therapeutics
FATE
$324M
$16.1M 4.41%
185,000
XENE icon
5
Xenon Pharmaceuticals
XENE
$6.6B
$15.8M 4.35%
850,000
ARVN icon
6
Arvinas
ARVN
$517M
$15.8M 4.34%
205,000
SNDX icon
7
Syndax Pharmaceuticals
SNDX
$2.02B
$15M 4.13%
875,000
-300,000
-26% -$5.49M
KURA icon
8
Kura Oncology
KURA
$964M
$14.6M 4.01%
700,000
+100,000
+17% +$2.48M
COGT icon
9
Cogent Biosciences
COGT
$6.68B
$13M 3.57%
1,600,000
TRIL
10
DELISTED
Trillium Therapeutics Inc.
TRIL
$12.1M 3.33%
1,250,000
-700,000
-36% -$6.59M
IOVA icon
11
Iovance Biotherapeutics
IOVA
$2.23B
$11.7M 3.22%
450,000
-50,000
-10% -$1.3M
BIIB icon
12
Biogen
BIIB
$30.4B
$11.3M 3.09%
32,500
+12,500
+63% +$3.79M
CLDX icon
13
Celldex Therapeutics
CLDX
$2.77B
$9.53M 2.62%
285,000
+35,000
+14% +$961K
MRTX
14
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$8.08M 2.22%
50,000
ALLO icon
15
Allogene Therapeutics
ALLO
$618M
$7.17M 1.97%
+275,000
New +$7.84M
TGTX icon
16
TG Therapeutics
TGTX
$8.4B
$6.98M 1.92%
180,000
-20,000
-10% -$785K
ALDX icon
17
Aldeyra Therapeutics
ALDX
$102M
$6.8M 1.87%
600,000
-50,000
-8% -$601K
VRNA
18
DELISTED
Verona Pharma
VRNA
$6.54M 1.8%
1,000,000
+60,957
+6% +$423K
VRDN icon
19
Viridian Therapeutics
VRDN
$1.99B
$6.4M 1.76%
350,000
+50,000
+17% +$856K
STSA
20
DELISTED
Satsuma Pharmaceuticals, Inc. Common Stock
STSA
$6.38M 1.75%
904,225
VTGN icon
21
VistaGen Therapeutics
VTGN
$9.4M
$6.3M 1.73%
66,667
-71,456
-52% -$5.29M
MRSN
22
DELISTED
Mersana Therapeutics
MRSN
$6.11M 1.68%
18,000
BCYC
23
Bicycle Therapeutics
BCYC
$294M
$6.07M 1.67%
200,000
+50,000
+33% +$1.51M
EPIX
24
DELISTED
ESSA Pharma
EPIX
$5.93M 1.63%
207,500
+32,500
+19% +$945K
RCKT icon
25
Rocket Pharmaceuticals
RCKT
$376M
$5.54M 1.52%
125,000
-200,000
-62% -$8.69M

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Ghost Tree Capital's Q2 2021 Portfolio in Review

As of Q2 2021, Ghost Tree Capital held 67 positions worth $364M, down 14% from $425M the previous quarter. Its ten largest holdings account for 49% of the portfolio.

Ghost Tree Capital withdrew a net $51.8M in Q2 2021, closing 14 positions and reducing 10 holdings. Its most notable exit was Apellis Pharmaceuticals, an estimated $9.65M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 85% of assets, up from 77% a quarter earlier.

Against the trend, Ghost Tree Capital opened a new position in RAPT Therapeutics worth $18.1M.

  • Ghost Tree Capital's largest Q2 2021 buy was RAPT Therapeutics: 71,250 shares worth $18.1M.
  • Ghost Tree Capital added most to Biogen in Q2 2021, an estimated $3.79M increase.
  • Ghost Tree Capital's biggest Q2 2021 reduction was Rocket Pharmaceuticals, cutting an estimated $8.69M.
  • Ghost Tree Capital fully exited Apellis Pharmaceuticals in Q2 2021, selling an estimated $9.65M.
  • Ghost Tree Capital's ten largest holdings make up 49% of its $364M portfolio in Q2 2021.
  • Ghost Tree Capital opened 17 new positions and closed 14 in Q2 2021.
  • Ghost Tree Capital's portfolio value fell 14% quarter-over-quarter to $364M.

Based on Ghost Tree Capital's 13F filing for Q2 2021, filed 11 Aug 2021.