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Ghost Tree Capital Portfolio holdings

AUM $331M
1-Year Est. Return 70.11%
This Fund
S&P 500
This Quarter Est. Return
+8.97%
1 Year Est. Return
+70.11%
3 Year Est. Return
+265.05%
5 Year Est. Return
+3,034.98%
10 Year Est. Return
+22,104.75%
AUM
$425M
AUM Growth
-$23.3M
Cap. Flow
+$28.2M
Cap. Flow %
6.64%
Top 10 Hldgs %
49.03%
Holding
60
New
17
Increased
11
Reduced
11
Closed
10
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
QQQ icon
1
PUT
Invesco QQQ Trust
QQQ
$466B
$47.9M 11.25%
150,000
+50,000
+50% +$16M
SNDX icon
2
Syndax Pharmaceuticals
SNDX
$2.02B
$26.3M 6.18%
1,175,000
-175,000
-13% -$3.95M
TRIL
3
DELISTED
Trillium Therapeutics Inc.
TRIL
$20.9M 4.92%
1,950,000
ARKG icon
4
PUT
ARK Genomic Revolution ETF
ARKG
$1.61B
$17.7M 4.17%
+200,000
New +$19.8M
ASND icon
5
Ascendis Pharma A/S
ASND
$17.1B
$17.4M 4.09%
135,000
+30,000
+29% +$4.56M
KURA icon
6
Kura Oncology
KURA
$964M
$17M 3.99%
600,000
+275,000
+85% +$8.7M
IOVA icon
7
Iovance Biotherapeutics
IOVA
$2.23B
$15.8M 3.72%
500,000
FATE icon
8
Fate Therapeutics
FATE
$324M
$15.3M 3.58%
185,000
+20,000
+12% +$1.92M
XENE icon
9
Xenon Pharmaceuticals
XENE
$6.6B
$15.2M 3.58%
850,000
+150,000
+21% +$2.54M
ACRS icon
10
Aclaris Therapeutics
ACRS
$793M
$15.1M 3.55%
600,000
-50,000
-8% -$978K
RCKT icon
11
Rocket Pharmaceuticals
RCKT
$376M
$14.4M 3.39%
325,000
-175,000
-35% -$9.61M
COGT icon
12
Cogent Biosciences
COGT
$6.68B
$14M 3.3%
1,600,000
+500,000
+45% +$4.81M
ARVN icon
13
Arvinas
ARVN
$517M
$13.6M 3.18%
205,000
APLS
14
DELISTED
Apellis Pharmaceuticals
APLS
$9.65M 2.27%
225,000
-100,000
-31% -$4.73M
TGTX icon
15
TG Therapeutics
TGTX
$8.4B
$9.64M 2.27%
200,000
-50,000
-20% -$2.4M
VTGN icon
16
VistaGen Therapeutics
VTGN
$9.4M
$8.83M 2.07%
138,123
+56,790
+70% +$3.79M
MRTX
17
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$8.56M 2.01%
50,000
VRNA
18
DELISTED
Verona Pharma
VRNA
$7.85M 1.85%
939,043
+129,043
+16% +$1.07M
ALDX icon
19
Aldeyra Therapeutics
ALDX
$102M
$7.72M 1.81%
650,000
MRSN
20
DELISTED
Mersana Therapeutics
MRSN
$7.28M 1.71%
18,000
-6,000
-25% -$2.91M
ISEE
21
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$6.95M 1.63%
1,125,000
-250,000
-18% -$1.52M
IWM icon
22
iShares Russell 2000 ETF
IWM
$82.2B
$6.63M 1.56%
+30,000
New +$6.55M
CNST
23
DELISTED
Constellation Pharmaceuticals, Inc.
CNST
$6.43M 1.51%
275,000
-350,000
-56% -$10.6M
BIIB icon
24
Biogen
BIIB
$30.4B
$5.59M 1.32%
20,000
+17,800
+809% +$4.8M
CLDX icon
25
Celldex Therapeutics
CLDX
$2.77B
$5.15M 1.21%
+250,000
New +$5.74M

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Ghost Tree Capital's Q1 2021 Portfolio in Review

As of Q1 2021, Ghost Tree Capital held 60 positions worth $425M, down 5.2% from $449M the previous quarter. Its ten largest holdings account for 49% of the portfolio.

Ghost Tree Capital deployed $28.2M of net new capital in Q1 2021, opening 17 new positions and adding to 11 existing holdings. Its largest new stake was iShares Russell 2000 ETF: 30,000 shares worth $6.63M.

By sector, the portfolio is most concentrated in Healthcare at 77% of assets, down from 83% a quarter earlier.

On the sell side, the largest reduction was Constellation Pharmaceuticals, Inc., an estimated $10.6M trimmed.

  • Ghost Tree Capital's largest Q1 2021 buy was iShares Russell 2000 ETF: 30,000 shares worth $6.63M.
  • Ghost Tree Capital added most to Kura Oncology in Q1 2021, an estimated $8.7M increase.
  • Ghost Tree Capital's biggest Q1 2021 reduction was Constellation Pharmaceuticals, Inc., cutting an estimated $10.6M.
  • Ghost Tree Capital fully exited Travere Therapeutics in Q1 2021, selling an estimated $12.9M.
  • Ghost Tree Capital's ten largest holdings make up 49% of its $425M portfolio in Q1 2021.
  • Ghost Tree Capital opened 17 new positions and closed 10 in Q1 2021.
  • Ghost Tree Capital's portfolio value fell 5.2% quarter-over-quarter to $425M.

Based on Ghost Tree Capital's 13F filing for Q1 2021, filed 14 May 2021.