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Ghost Tree Capital Portfolio holdings

AUM $331M
1-Year Est. Return 70.11%
This Fund
S&P 500
This Quarter Est. Return
+28.76%
1 Year Est. Return
+70.11%
3 Year Est. Return
+265.05%
5 Year Est. Return
+3,034.98%
10 Year Est. Return
+22,104.75%
AUM
$361M
AUM Growth
+$55.4M
Cap. Flow
+$39.7M
Cap. Flow %
10.98%
Top 10 Hldgs %
40.07%
Holding
85
New
33
Increased
24
Reduced
13
Closed
13
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
XBI icon
1
PUT
State Street SPDR S&P Biotech ETF
XBI
$10.4B
$23.7M 6.57%
250,000
-50,000
-17% -$4.64M
AXSM icon
2
Axsome Therapeutics
AXSM
$11.8B
$16.8M 4.64%
210,000
+45,000
+27% +$3.78M
SRPT icon
3
Sarepta Therapeutics
SRPT
$1.82B
$16.2M 4.48%
125,000
+25,000
+25% +$3.06M
BHVN icon
4
Biohaven
BHVN
$2.32B
$15.6M 4.31%
285,000
+10,000
+4% +$495K
MLTX icon
5
MoonLake Immunotherapeutics
MLTX
$1.64B
$15.1M 4.17%
300,000
+220,000
+275% +$11.9M
ROIV icon
6
Roivant Sciences
ROIV
$24.8B
$13.7M 3.79%
1,300,000
+700,000
+117% +$7.55M
TGTX icon
7
TG Therapeutics
TGTX
$8.4B
$12.5M 3.47%
825,000
+575,000
+230% +$9.16M
VRDN icon
8
Viridian Therapeutics
VRDN
$1.99B
$10.9M 3.03%
625,000
+325,000
+108% +$6.3M
TARS icon
9
Tarsus Pharmaceuticals
TARS
$2.61B
$10.9M 3.02%
300,000
CRNX icon
10
Crinetics Pharmaceuticals
CRNX
$8.88B
$9.36M 2.59%
200,000
+135,000
+208% +$5.28M
ALNY icon
11
Alnylam Pharmaceuticals
ALNY
$35.7B
$8.97M 2.48%
60,000
+32,500
+118% +$5.42M
SLNO
12
DELISTED
Soleno Therapeutics
SLNO
$8.56M 2.37%
200,000
+87,615
+78% +$3.96M
SVRA icon
13
Savara
SVRA
$1.13B
$7.97M 2.21%
1,600,000
+850,000
+113% +$4.11M
APLS
14
DELISTED
Apellis Pharmaceuticals
APLS
$7.64M 2.12%
+130,000
New +$8.29M
CATX icon
15
Perspective Therapeutics
CATX
$341M
$7.14M 1.98%
600,000
+440,000
+275% +$3.75M
BPMC
16
DELISTED
Blueprint Medicines
BPMC
$6.9M 1.91%
+72,761
New +$6.24M
JBIO
17
Jade Biosciences
JBIO
$1.27B
$6.65M 1.84%
6,429
+429
+7% +$328K
VKTX icon
18
CALL
Viking Therapeutics
VKTX
$4.31B
$6.56M 1.82%
+80,000
New +$3.56M
PCVX icon
19
Vaxcyte
PCVX
$8.12B
$6.49M 1.8%
95,000
+25,000
+36% +$1.73M
CABA icon
20
Cabaletta Bio
CABA
$461M
$6.4M 1.77%
375,000
+225,000
+150% +$4.83M
VKTX icon
21
Viking Therapeutics
VKTX
$4.31B
$5.99M 1.66%
+73,002
New +$3.25M
RYTM icon
22
Rhythm Pharmaceuticals
RYTM
$7.31B
$5.42M 1.5%
+125,000
New +$5.47M
BBIO icon
23
BridgeBio Pharma
BBIO
$15.9B
$5.41M 1.5%
175,000
+50,000
+40% +$1.7M
REPL icon
24
Replimune Group
REPL
$859M
$5.31M 1.47%
650,000
+250,000
+63% +$2.05M
CYTK icon
25
CALL
Cytokinetics
CYTK
$10.9B
$5.26M 1.46%
75,000
-5,000
-6% -$387K

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Ghost Tree Capital's Q1 2024 Portfolio in Review

As of Q1 2024, Ghost Tree Capital held 85 positions worth $361M, up 18% from $306M the previous quarter. Its ten largest holdings account for 40% of the portfolio.

Ghost Tree Capital deployed $39.7M of net new capital in Q1 2024, opening 33 new positions and adding to 24 existing holdings. Its largest new stake was Apellis Pharmaceuticals: 130,000 shares worth $7.64M.

By sector, the portfolio is most concentrated in Healthcare at 85% of assets, up from 56% a quarter earlier.

On the sell side, the largest reduction was Krystal Biotech, an estimated $5M trimmed.

  • Ghost Tree Capital's largest Q1 2024 buy was Apellis Pharmaceuticals: 130,000 shares worth $7.64M.
  • Ghost Tree Capital added most to MoonLake Immunotherapeutics in Q1 2024, an estimated $11.9M increase.
  • Ghost Tree Capital's biggest Q1 2024 reduction was Krystal Biotech, cutting an estimated $5M.
  • Ghost Tree Capital fully exited Ambrx Biopharma Inc in Q1 2024, selling an estimated $6.76M.
  • Ghost Tree Capital's ten largest holdings make up 40% of its $361M portfolio in Q1 2024.
  • Ghost Tree Capital opened 33 new positions and closed 13 in Q1 2024.
  • Ghost Tree Capital's portfolio value rose 18% quarter-over-quarter to $361M.

Based on Ghost Tree Capital's 13F filing for Q1 2024, filed 15 May 2024.