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Ghost Tree Capital Portfolio holdings

AUM $331M Turnover 44%
1-Year Est. Return 70.11%
This Fund
S&P 500
This Quarter Est. Return
+14.65%
1 Year Est. Return
+70.11%
3 Year Est. Return
+265.05%
5 Year Est. Return
+3,034.98%
10 Year Est. Return
+22,104.75%
AUM
$331M
AUM Growth
+$11.7M
Cap. Flow
-$38.1M
Cap. Flow %
-11.51%
Top 10 Hldgs %
42.42%
Holding
75
New
12
Increased
16
Reduced
23
Closed
21
Avg Time Held Equity + Options
0.7 years
Top 10 Avg Time Held Equity + Options
0.2 years
Top 20 Avg Time Held Equity + Options
0.4 years
Avg Time Held Equity only
0.8 years
Top 10 Avg Time Held Equity only
0.2 years
Top 20 Avg Time Held Equity only
0.8 years

Sector Composition

Rank Sector Weight
1 Healthcare 83.31%
2 Miscellaneous 16.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
REPL icon
26
Replimune Group
REPL
$1.04B
$4.93M 1.49%
450,000
– –
2023 Q4
3 quarters
CRBP icon
27
PUT
Corbus Pharmaceuticals
CRBP
$86.3M
$4.54M 1.37%
+220,000
New +$11.3M
2024 Q3
0 quarters
BBIO icon
28
BridgeBio Pharma
BBIO
$13.3B
$4.46M 1.35%
175,000
+35,000
+25% +$919K
2023 Q1
6 quarters
TSHA icon
29
Taysha Gene Therapies
TSHA
$1.28B
$4.32M 1.31%
2,150,000
+900,000
+72% +$1.97M
2023 Q3
4 quarters
RYTM icon
30
Rhythm Pharmaceuticals
RYTM
$6.07B
$4.13M 1.25%
78,842
-38,546
-33% -$1.85M
2024 Q1
2 quarters
ANNX icon
31
Annexon
ANNX
$760M
$3.85M 1.16%
650,000
+340,000
+110% +$2.02M
2024 Q2
1 quarter
KRRO icon
32
Korro Bio
KRRO
$131M
$3.68M 1.11%
110,000
+10,000
+10% +$421K
2024 Q2
1 quarter
INSM icon
33
CALL
Insmed
INSM
$20.8B
$3.65M 1.1%
50,000
-150,000
-75% -$11.1M
2024 Q2
1 quarter
DYN icon
34
Dyne Therapeutics
DYN
$2.84B
$3.59M 1.09%
+100,000
New +$3.98M
2024 Q3
0 quarters
ARVN icon
35
Arvinas
ARVN
$475M
$3.57M 1.08%
145,000
+70,000
+93% +$1.83M
2023 Q4
3 quarters
CRBP icon
36
Corbus Pharmaceuticals
CRBP
$86.3M
$3.3M 1%
160,000
-15,000
-9% -$768K
2024 Q1
2 quarters
BBOT icon
37
BridgeBio Oncology
BBOT
$228M
$3.13M 0.95%
300,000
– –
2024 Q1
2 quarters
NUVB icon
38
Nuvation Bio
NUVB
$1.57B
$3.09M 0.93%
1,350,000
+200,000
+17% +$610K
2024 Q2
1 quarter
SVRA icon
39
Savara
SVRA
$951M
$3.07M 0.93%
725,000
-325,876
-31% -$1.44M
2023 Q4
3 quarters
TNYA icon
40
Tenaya Therapeutics
TNYA
$84.7M
$2.9M 0.87%
1,500,000
+150,000
+11% +$423K
2024 Q1
2 quarters
RGNX icon
41
Regenxbio
RGNX
$472M
$2.78M 0.84%
265,000
+95,000
+56% +$1.16M
2024 Q1
2 quarters
CRVS icon
42
Corvus Pharmaceuticals
CRVS
$812M
$2.64M 0.8%
+500,000
New +$1.8M
2024 Q3
0 quarters
ABSI icon
43
Absci
ABSI
$1.47B
$2.1M 0.63%
+550,000
New +$2.19M
2024 Q3
0 quarters
NGNE icon
44
Neurogene
NGNE
$484M
$2.1M 0.63%
50,000
-20,000
-29% -$776K
2024 Q1
2 quarters
CAPR icon
45
Capricor Therapeutics
CAPR
$387M
$1.9M 0.57%
+125,000
New +$618K
2024 Q3
0 quarters
APLS icon
46
DELISTED
Apellis Pharmaceuticals
APLS
$1.87M 0.57%
65,000
-70,000
-52% -$2.59M
2024 Q1
2 quarters
SMMT icon
47
Summit Therapeutics
SMMT
$12.4B
$1.86M 0.56%
+85,000
New +$1.19M
2024 Q3
0 quarters
SYRE icon
48
Spyre Therapeutics
SYRE
$7.92B
$1.76M 0.53%
60,000
-190,237
-76% -$5.3M
2024 Q1
2 quarters
VRDN icon
49
Viridian Therapeutics
VRDN
$2.36B
$1.71M 0.52%
75,000
-512,708
-87% -$8.38M
2021 Q1
14 quarters
PRQR icon
50
ProQR Therapeutics
PRQR
$185M
$1.62M 0.49%
887,700
-12,300
-1% -$23.1K
2024 Q2
1 quarter

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Ghost Tree Capital's Q3 2024 Portfolio in Review

As of Q3 2024, Ghost Tree Capital held 75 positions worth $331M, up 3.7% from $319M the previous quarter. Its ten largest holdings account for 42% of the portfolio.

Ghost Tree Capital withdrew a net $38.1M in Q3 2024, closing 21 positions and reducing 23 holdings. Its most notable exit was Biohaven, an estimated $19.1M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 83% of assets, down from 90% a quarter earlier, followed by Miscellaneous.

Against the trend, Ghost Tree Capital opened a new position in Novo Nordisk worth $13.1M.

  • Ghost Tree Capital's largest Q3 2024 buy was Novo Nordisk: 110,000 shares worth $13.1M.
  • Ghost Tree Capital added most to Blueprint Medicines in Q3 2024, an estimated $9.9M increase.
  • Ghost Tree Capital's biggest Q3 2024 reduction was Viridian Therapeutics, cutting an estimated $8.38M.
  • Ghost Tree Capital fully exited Biohaven in Q3 2024, selling an estimated $19.1M.
  • Ghost Tree Capital's ten largest holdings make up 42% of its $331M portfolio in Q3 2024.
  • Ghost Tree Capital opened 12 new positions and closed 21 in Q3 2024.
  • Ghost Tree Capital's portfolio value rose 3.7% quarter-over-quarter to $331M.

Based on Ghost Tree Capital's 13F filing for Q3 2024, filed 14 Nov 2024.