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EcoR1 Capital Portfolio holdings

AUM $2.36B
1-Year Est. Return 204.53%
This Fund
S&P 500
This Quarter Est. Return
-12.61%
1 Year Est. Return
+204.53%
3 Year Est. Return
+306.25%
5 Year Est. Return
+490.45%
10 Year Est. Return
+14,115.48%
AUM
$2.9B
AUM Growth
-$300M
Cap. Flow
+$226M
Cap. Flow %
7.79%
Top 10 Hldgs %
60.65%
Holding
101
New
14
Increased
15
Reduced
4
Closed
21

Top Buys

Rank Stock Value
1
SGEN
Seagen Inc. Common Stock
SGEN
+$145M
2
ARVN icon
Arvinas
ARVN
+$81.3M
3
SRPT icon
Sarepta Therapeutics
SRPT
+$58.7M
4
RVMD icon
Revolution Medicines
RVMD
+$58.5M
5
ALLO icon
Allogene Therapeutics
ALLO
+$39.8M

Top Sells

Rank Stock Value
1
RCUS icon
Arcus Biosciences
RCUS
+$103M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$41.2M
3
PCVX icon
Vaxcyte
PCVX
+$31.5M
4
BCYC
Bicycle Therapeutics
BCYC
+$24M
5
EXEL icon
Exelixis
EXEL
+$19.6M

Sector Composition

Rank Sector Weight
1 Healthcare 98.48%
2 Financials 0.68%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
RDUS
101
DELISTED
Radius Health, Inc.
RDUS
– –
-35,000
Closed -$309K
1 2 3 4
5

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EcoR1 Capital's Q2 2022 Portfolio in Review

As of Q2 2022, EcoR1 Capital held 101 positions worth $2.9B, down 9.4% from $3.2B the previous quarter. Its ten largest holdings account for 61% of the portfolio.

EcoR1 Capital deployed $226M of net new capital in Q2 2022, opening 14 new positions and adding to 15 existing holdings. Its largest new stake was Seagen Inc. Common Stock: 1,008,628 shares worth $178M.

By sector, the portfolio is most concentrated in Healthcare at 98% of assets, down from 99% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Alector, an estimated $16.8M trimmed.

  • EcoR1 Capital's largest Q2 2022 buy was Seagen Inc. Common Stock: 1,008,628 shares worth $178M.
  • EcoR1 Capital added most to Arvinas in Q2 2022, an estimated $81.3M increase.
  • EcoR1 Capital's biggest Q2 2022 reduction was Alector, cutting an estimated $16.8M.
  • EcoR1 Capital fully exited Arcus Biosciences in Q2 2022, selling an estimated $103M.
  • EcoR1 Capital's ten largest holdings make up 61% of its $2.9B portfolio in Q2 2022.
  • EcoR1 Capital opened 14 new positions and closed 21 in Q2 2022.
  • EcoR1 Capital's portfolio value fell 9.4% quarter-over-quarter to $2.9B.

Based on EcoR1 Capital's 13F filing for Q2 2022, filed 15 Aug 2022.