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EcoR1 Capital Portfolio holdings

AUM $2.36B
1-Year Est. Return 204.53%
This Fund
S&P 500
This Quarter Est. Return
+42.67%
1 Year Est. Return
+204.53%
3 Year Est. Return
+306.25%
5 Year Est. Return
+490.45%
10 Year Est. Return
+14,115.48%
AUM
$1.86B
AUM Growth
+$458M
Cap. Flow
+$125M
Cap. Flow %
6.71%
Top 10 Hldgs %
60.44%
Holding
79
New
30
Increased
3
Reduced
8
Closed
14

Top Buys

Rank Stock Value
1
SPRY icon
ARS Pharmaceuticals
SPRY
+$84.6M
2
STTK icon
Shattuck Labs
STTK
+$79M
3
SLDB icon
Solid Biosciences
SLDB
+$33.6M
4
KDNY
Chinook Therapeutics, Inc. Common Stock
KDNY
+$18.9M
5
ORIC icon
Oric Pharmaceuticals
ORIC
+$12.9M

Top Sells

Rank Stock Value
1
KURA icon
Kura Oncology
KURA
+$99.6M
2
STRO icon
Sutro Biopharma
STRO
+$50M
3
SURF
Surface Oncology, Inc. Common Stock
SURF
+$28.5M
4
ASMB icon
Assembly Biosciences
ASMB
+$24.9M
5
CBIO
Crescent Biopharma
CBIO
+$11.4M

Sector Composition

Rank Sector Weight
1 Healthcare 93.73%
2 Financials 0.51%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DFHTU
76
DELISTED
Deerfield Healthcare Technology Acquisitions Corp. Unit
DFHTU
– –
-500,000
Closed -$5.32M
FPRX
77
DELISTED
Five Prime Therapeutics, Inc.
FPRX
– –
-379,945
Closed -$1.79M
FSDC
78
DELISTED
FS Development Corp. Class A Common Stock
FSDC
– –
-350,000
Closed -$3.92M
1 2 3
4

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EcoR1 Capital's Q4 2020 Portfolio in Review

As of Q4 2020, EcoR1 Capital held 79 positions worth $1.86B, up 33% from $1.4B the previous quarter. Its ten largest holdings account for 60% of the portfolio.

EcoR1 Capital deployed $125M of net new capital in Q4 2020, opening 30 new positions and adding to 3 existing holdings. Its largest new stake was ARS Pharmaceuticals: 2,533,635 shares worth $117M.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, down from 96% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Kura Oncology, an estimated $99.6M trimmed.

  • EcoR1 Capital's largest Q4 2020 buy was ARS Pharmaceuticals: 2,533,635 shares worth $117M.
  • EcoR1 Capital added most to Oric Pharmaceuticals in Q4 2020, an estimated $12.9M increase.
  • EcoR1 Capital's biggest Q4 2020 reduction was Kura Oncology, cutting an estimated $99.6M.
  • EcoR1 Capital fully exited Assembly Biosciences in Q4 2020, selling an estimated $24.9M.
  • EcoR1 Capital's ten largest holdings make up 60% of its $1.86B portfolio in Q4 2020.
  • EcoR1 Capital opened 30 new positions and closed 14 in Q4 2020.
  • EcoR1 Capital's portfolio value rose 33% quarter-over-quarter to $1.86B.

Based on EcoR1 Capital's 13F filing for Q4 2020, filed 16 Feb 2021.