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EcoR1 Capital Portfolio holdings

AUM $2.36B
1-Year Est. Return 204.53%
This Fund
S&P 500
This Quarter Est. Return
-12.44%
1 Year Est. Return
+204.53%
3 Year Est. Return
+306.25%
5 Year Est. Return
+490.45%
10 Year Est. Return
+14,115.48%
AUM
$3.27B
AUM Growth
-$685M
Cap. Flow
+$6.49M
Cap. Flow %
0.2%
Top 10 Hldgs %
61.39%
Holding
65
New
6
Increased
5
Reduced
5
Closed
10

Top Buys

Rank Stock Value
1
MORF
Morphic Holding, Inc. Common Stock
MORF
+$77M
2
JANX icon
Janux Therapeutics
JANX
+$69M
3
CRGX
CARGO Therapeutics
CRGX
+$27.9M
4
BCYC
Bicycle Therapeutics
BCYC
+$20.6M
5
ITOS
iTeos Therapeutics
ITOS
+$17.9M

Top Sells

Rank Stock Value
1
ACAD icon
Acadia Pharmaceuticals
ACAD
+$75M
2
SRPT icon
Sarepta Therapeutics
SRPT
+$65.8M
3
ALEC icon
Alector
ALEC
+$24.4M
4
NKTX icon
Nkarta
NKTX
+$21.6M
5
OVID icon
Ovid Therapeutics
OVID
+$18.7M

Sector Composition

Rank Sector Weight
1 Healthcare 99.88%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KYTX icon
51
Kyverna Therapeutics
KYTX
$450M
$3.38M 0.1%
450,000
– –
NUVB.WS
52
DELISTED
Nuvation Bio Inc Warrants
NUVB.WS
$2.81M 0.09%
963,333
– –
ALGS icon
53
Aligos Therapeutics
ALGS
$25.2M
$2.24M 0.07%
255,579
– –
SRZNW icon
54
Surrozen Inc Warrant
SRZNW
$49.5K
$730K 0.02%
66,665
– –
CMAXW
55
DELISTED
CareMax, Inc. Warrant
CMAXW
$279K 0.01%
100,000
– –
ALEC icon
56
Alector
ALEC
$164M
– –
-4,056,548
Closed -$24.4M
ARQT icon
57
Arcutis Biotherapeutics
ARQT
$3.42B
– –
-500,000
Closed -$4.96M
GOSS icon
58
Gossamer Bio
GOSS
$66.5M
– –
-9,195,404
Closed -$10.9M
KOD icon
59
CALL
Kodiak Sciences
KOD
$2.59B
– –
-51,100
Closed -$269K
KOD icon
60
Kodiak Sciences
KOD
$2.59B
– –
-1,613,600
Closed -$8.49M
KURA icon
61
CALL
Kura Oncology
KURA
$922M
– –
-700,000
Closed -$14.9M
NKTX icon
62
Nkarta
NKTX
$162M
– –
-2,000,000
Closed -$21.6M
OVID icon
63
Ovid Therapeutics
OVID
$435M
– –
-6,117,400
Closed -$18.7M
PMVP icon
64
PMV Pharmaceuticals
PMVP
$66.1M
– –
-566,879
Closed -$964K
ALPN
65
DELISTED
Alpine Immune Sciences Inc
ALPN
– –
-1,000
Closed -$39.6K
1 2
3

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EcoR1 Capital's Q2 2024 Portfolio in Review

As of Q2 2024, EcoR1 Capital held 65 positions worth $3.27B, down 17% from $3.95B the previous quarter. Its ten largest holdings account for 61% of the portfolio.

EcoR1 Capital's Q2 2024 filing shows 6 new, 5 increased, 5 reduced and 10 closed positions. Its largest new stake was Janux Therapeutics: 1,469,818 shares worth $61.6M. The largest sale was Acadia Pharmaceuticals, an estimated $75M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 99% a quarter earlier.

  • EcoR1 Capital's largest Q2 2024 buy was Janux Therapeutics: 1,469,818 shares worth $61.6M.
  • EcoR1 Capital added most to Morphic Holding, Inc. Common Stock in Q2 2024, an estimated $77M increase.
  • EcoR1 Capital's biggest Q2 2024 reduction was Acadia Pharmaceuticals, cutting an estimated $75M.
  • EcoR1 Capital fully exited Alector in Q2 2024, selling an estimated $24.4M.
  • EcoR1 Capital's ten largest holdings make up 61% of its $3.27B portfolio in Q2 2024.
  • EcoR1 Capital opened 6 new positions and closed 10 in Q2 2024.
  • EcoR1 Capital's portfolio value fell 17% quarter-over-quarter to $3.27B.

Based on EcoR1 Capital's 13F filing for Q2 2024, filed 14 Aug 2024.