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EcoR1 Capital Portfolio holdings

AUM $2.36B
1-Year Est. Return 204.53%
This Fund
S&P 500
This Quarter Est. Return
+10.16%
1 Year Est. Return
+204.53%
3 Year Est. Return
+306.25%
5 Year Est. Return
+490.45%
10 Year Est. Return
+14,115.48%
AUM
$2.87B
AUM Growth
+$199M
Cap. Flow
+$85.5M
Cap. Flow %
2.97%
Top 10 Hldgs %
71.68%
Holding
83
New
11
Increased
14
Reduced
8
Closed
12

Top Buys

Rank Stock Value
1
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$92.5M
2
PTGX icon
Protagonist Therapeutics
PTGX
+$61.6M
3
RCUS icon
Arcus Biosciences
RCUS
+$55.6M
4
DRNA
Dicerna Pharmaceuticals, Inc.
DRNA
+$34.5M
5
ALEC icon
Alector
ALEC
+$21.1M

Top Sells

Rank Stock Value
1
RLAY icon
Relay Therapeutics
RLAY
+$104M
2
SPRY icon
ARS Pharmaceuticals
SPRY
+$35.3M
3
TBIO
Translate Bio, Inc. Common Stock
TBIO
+$28.9M
4
NRIX icon
Nurix Therapeutics
NRIX
+$26M
5
KYMR icon
Kymera Therapeutics
KYMR
+$25.2M

Sector Composition

Rank Sector Weight
1 Healthcare 96.93%
2 Financials 0.68%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BLSA
51
DELISTED
BCLS Acquisition Corp. Class A Ordinary Shares
BLSA
$1.99M 0.07%
200,000
– –
MLTX icon
52
MoonLake Immunotherapeutics
MLTX
$1.61B
$1.99M 0.07%
200,000
– –
FVAM
53
DELISTED
5:01 Acquisition Corp
FVAM
$1.96M 0.07%
200,000
– –
EUCR
54
DELISTED
Eucrates Biomedical Acquisition Corp. Ordinary Shares
EUCR
$1.96M 0.07%
200,000
– –
BOLT icon
55
Bolt Biotherapeutics
BOLT
$7.78M
$1.85M 0.06%
7,500
– –
CRBU icon
56
Caribou Biosciences
CRBU
$146M
$1.79M 0.06%
+75,000
New +$1.83M
ARYD
57
DELISTED
ARYA Sciences Acquisition Corp IV Class A Odinary Shares
ARYD
$1.51M 0.05%
150,000
– –
PMVP icon
58
PMV Pharmaceuticals
PMVP
$58.7M
$1.49M 0.05%
50,000
– –
BCAB icon
59
BioAtla
BCAB
$5.63M
$1.47M 0.05%
1,000
– –
RPTX
60
DELISTED
Repare Therapeutics
RPTX
$1.29M 0.04%
50,000
– –
MGTX icon
61
MeiraGTx Holdings
MGTX
$1.09B
$1.25M 0.04%
94,819
– –
VYGR icon
62
Voyager Therapeutics
VYGR
$181M
$1.17M 0.04%
+445,992
New +$1.45M
CMAXW
63
DELISTED
CareMax, Inc. Warrant
CMAXW
$986K 0.03%
100,000
– –
TMPM
64
DELISTED
Turmeric Acquisition Corp. Class A Ordinary Shares
TMPM
$979K 0.03%
100,000
– –
FLACW
65
DELISTED
Frazier Lifesciences Acquisition Corporation Warrant
FLACW
$655K 0.02%
66,665
– –
EUCRW
66
DELISTED
Eucrates Biomedical Acquisition Corp. Warrant
EUCRW
$652K 0.02%
66,666
– –
OMEG
67
DELISTED
Omega Alpha SPAC Class A Ordinary Shares
OMEG
$487K 0.02%
50,000
– –
SRZNW icon
68
Surrozen Inc Warrant
SRZNW
$75.6K
$471K 0.02%
66,665
– –
TMPMW
69
DELISTED
Turmeric Acquisition Corp. Warrant
TMPMW
$326K 0.01%
33,333
– –
SRRK icon
70
Scholar Rock
SRRK
$5.83B
$271K 0.01%
+8,208
New +$287K
ALPN
71
DELISTED
Alpine Immune Sciences Inc
ALPN
$75K ﹤0.01%
7,001
-515,634
-99% -$4.75M
ARVN icon
72
Arvinas
ARVN
$526M
– –
-321,724
Closed -$24.8M
DNTH icon
73
Dianthus Therapeutics
DNTH
$5.58B
– –
-22,929
Closed -$3.59M
KYMR icon
74
Kymera Therapeutics
KYMR
$8.77B
– –
-519,416
Closed -$25.2M
SRZN icon
75
Surrozen
SRZN
$225M
– –
-13,333
Closed -$1.99M
1 2
3
4

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EcoR1 Capital's Q3 2021 Portfolio in Review

As of Q3 2021, EcoR1 Capital held 83 positions worth $2.87B, up 7.4% from $2.68B the previous quarter. Its ten largest holdings account for 72% of the portfolio.

EcoR1 Capital's Q3 2021 filing shows 11 new, 14 increased, 8 reduced and 12 closed positions. Its largest new stake was Lakefront Biotherapeutics American Depositary Shares: 1,558,749 shares worth $82M. The largest sale was Relay Therapeutics, an estimated $104M.

By sector, the portfolio is most concentrated in Healthcare at 97% of assets, down from 99% a quarter earlier, followed by Financials.

  • EcoR1 Capital's largest Q3 2021 buy was Lakefront Biotherapeutics American Depositary Shares: 1,558,749 shares worth $82M.
  • EcoR1 Capital added most to Arcus Biosciences in Q3 2021, an estimated $55.6M increase.
  • EcoR1 Capital's biggest Q3 2021 reduction was Relay Therapeutics, cutting an estimated $104M.
  • EcoR1 Capital fully exited Translate Bio, Inc. Common Stock in Q3 2021, selling an estimated $28.9M.
  • EcoR1 Capital's ten largest holdings make up 72% of its $2.87B portfolio in Q3 2021.
  • EcoR1 Capital opened 11 new positions and closed 12 in Q3 2021.
  • EcoR1 Capital's portfolio value rose 7.4% quarter-over-quarter to $2.87B.

Based on EcoR1 Capital's 13F filing for Q3 2021, filed 15 Nov 2021.