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EcoR1 Capital Portfolio holdings

AUM $2.06B
1-Year Est. Return 215.32%
This Fund
S&P 500
This Quarter Est. Return
+10.75%
1 Year Est. Return
+215.32%
3 Year Est. Return
+310.3%
5 Year Est. Return
+497.45%
10 Year Est. Return
+14,692.23%
AUM
$888M
AUM Growth
+$138M
Cap. Flow
-$23.2M
Cap. Flow %
-2.62%
Top 10 Hldgs %
78.6%
Holding
52
New
13
Increased
8
Reduced
4
Closed
22

Top Buys

Rank Stock Value
1
DRNA
Dicerna Pharmaceuticals, Inc.
DRNA
+$28.5M
2
MGNX icon
MacroGenics
MGNX
+$21.3M
3
IMDZ
Immune Design Corp.
IMDZ
+$19.4M
4
ARRY
Array Biopharma Inc
ARRY
+$18.6M
5
APLS
Apellis Pharmaceuticals
APLS
+$16.8M

Top Sells

Rank Stock Value
1
IMMU
Immunomedics Inc
IMMU
+$40M
2
MRNS
Marinus Pharmaceuticals, Inc
MRNS
+$21.3M
3
FBRX icon
Forte Biosciences
FBRX
+$18.7M
4
CTMX icon
CytomX Therapeutics
CTMX
+$15.1M
5
INDP icon
Indaptus Therapeutics
INDP
+$13.4M

Sector Composition

Rank Sector Weight
1 Healthcare 83.97%
2 Miscellaneous 16.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
IMMU
51
DELISTED
Immunomedics Inc
IMMU
– –
-2,860,019
Closed -$40M
CASC
52
DELISTED
Cascadian Therapeutics, Inc.
CASC
– –
-3,000,000
Closed -$12.3M
1 2
3

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EcoR1 Capital's Q4 2017 Portfolio in Review

As of Q4 2017, EcoR1 Capital held 52 positions worth $888M, up 18% from $750M the previous quarter. Its ten largest holdings account for 79% of the portfolio.

EcoR1 Capital's Q4 2017 filing shows 13 new, 8 increased, 4 reduced and 22 closed positions. Its largest new stake was MacroGenics: 1,140,794 shares worth $21.7M. The largest sale was Immunomedics Inc, an estimated $40M.

By sector, the portfolio is most concentrated in Healthcare at 84% of assets, down from 97% a quarter earlier, followed by Miscellaneous.

  • EcoR1 Capital's largest Q4 2017 buy was MacroGenics: 1,140,794 shares worth $21.7M.
  • EcoR1 Capital added most to Dicerna Pharmaceuticals, Inc. in Q4 2017, an estimated $28.5M increase.
  • EcoR1 Capital's biggest Q4 2017 reduction was Lakefront Biotherapeutics American Depositary Shares, cutting an estimated $12.3M.
  • EcoR1 Capital fully exited Immunomedics Inc in Q4 2017, selling an estimated $40M.
  • EcoR1 Capital's ten largest holdings make up 79% of its $888M portfolio in Q4 2017.
  • EcoR1 Capital opened 13 new positions and closed 22 in Q4 2017.
  • EcoR1 Capital's portfolio value rose 18% quarter-over-quarter to $888M.

Based on EcoR1 Capital's 13F filing for Q4 2017, filed 14 Feb 2018.