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EcoR1 Capital Portfolio holdings

AUM $2.06B Turnover 46.34%
1-Year Est. Return 215.32%
This Fund
S&P 500
This Quarter Est. Return
+30.44%
1 Year Est. Return
+215.32%
3 Year Est. Return
+310.3%
5 Year Est. Return
+497.45%
10 Year Est. Return
+14,692.23%
AUM
$318M
AUM Growth
+$98.7M
Cap. Flow
+$13.5M
Cap. Flow %
4.23%
Top 10 Hldgs %
67.71%
Holding
36
New
11
Increased
7
Reduced
7
Closed
5
Avg Time Held Equity + Options
0.4 years
Top 10 Avg Time Held Equity + Options
0.3 years
Top 20 Avg Time Held Equity + Options
0.5 years
Avg Time Held Equity only
0.5 years
Top 10 Avg Time Held Equity only
0.4 years
Top 20 Avg Time Held Equity only
0.6 years

Sector Composition

Rank Sector Weight
1 Healthcare 77.71%
2 Miscellaneous 22.29%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
AKTX icon
26
Akari Therapeutics
AKTX
$20.2M
$1.46M 0.46%
126
– –
2015 Q3
1 quarter
GILD icon
27
CALL
Gilead Sciences
GILD
$195B
$1.19M 0.38%
11,800
+8,545
+263% +$889K
2015 Q3
1 quarter
NRX
28
DELISTED
NEPHROGENEX INC COM
NRX
$941K 0.3%
+588,235
New +$1.37M
2015 Q4
0 quarters
QLTI icon
29
DELISTED
QLT Inc
QLTI
$266K 0.08%
100,000
-538,900
-84% -$1.52M
2015 Q2
2 quarters
LRMR icon
30
CALL
Larimar Therapeutics
LRMR
$207M
$63K 0.02%
+833
New +$134K
2015 Q4
0 quarters
ATRA icon
31
Atara Biotherapeutics
ATRA
$96.9M
– –
-32,138
Closed -$25.3M –
GYRE icon
32
Gyre Therapeutics
GYRE
$679M
– –
-498
Closed -$261K –
RGLS icon
33
CALL
DELISTED
Regulus Therapeutics
RGLS
– –
-11
Closed -$35K –
CASC
34
DELISTED
Cascadian Therapeutics, Inc.
CASC
– –
-157,250
Closed -$2.58M –
OREX
35
DELISTED
Orexigen Therapeutics, Inc.
OREX
– –
-93,796
Closed -$1.98M –

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EcoR1 Capital's Q4 2015 Portfolio in Review

As of Q4 2015, EcoR1 Capital held 36 positions worth $318M, up 45% from $220M the previous quarter. Its ten largest holdings account for 68% of the portfolio.

EcoR1 Capital deployed $13.5M of net new capital in Q4 2015, opening 11 new positions and adding to 7 existing holdings. Its largest new stake was Kura Oncology: 2,450,000 shares worth $20.6M.

By sector, the portfolio is most concentrated in Healthcare at 78% of assets, down from 88% a quarter earlier, followed by Miscellaneous.

On the sell side, the largest reduction was Epizyme, Inc, an estimated $11.8M trimmed.

  • EcoR1 Capital's largest Q4 2015 buy was Kura Oncology: 2,450,000 shares worth $20.6M.
  • EcoR1 Capital added most to Five Prime Therapeutics, Inc. in Q4 2015, an estimated $19.1M increase.
  • EcoR1 Capital's biggest Q4 2015 reduction was Epizyme, Inc, cutting an estimated $11.8M.
  • EcoR1 Capital fully exited Atara Biotherapeutics in Q4 2015, selling an estimated $25.3M.
  • EcoR1 Capital's ten largest holdings make up 68% of its $318M portfolio in Q4 2015.
  • EcoR1 Capital opened 11 new positions and closed 5 in Q4 2015.
  • EcoR1 Capital's portfolio value rose 45% quarter-over-quarter to $318M.

Based on EcoR1 Capital's 13F filing for Q4 2015, filed 16 Feb 2016.