DP
UPB

Diadema Partners’s Upstream Bio Inc UPB Stock Holding History

Diadema Partners’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$132K Sell
19,093
-2,516
-12% -$21.1K 0.02% 134
2026
Q1 		$194K Buy
21,609
+1,109
+5% +$20K 0.03% 125
2025
Q4 		$557K Buy
+20,500
New +$510K 0.1% 111

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Diadema Partners's UPB Position: Q2 2026 in Review

Diadema Partners reduced its Upstream Bio Inc (UPB) stake by 12% in Q2 2026, selling an estimated $21.1K and leaving 19,093 shares worth $132K. The position accounts for 0.02% of the portfolio, ranked #134.

Diadema Partners first reported a position in UPB in Q4 2025 and has held it in 3 quarters since. The position peaked at $557K in Q4 2025. 149 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Diadema Partners held 19,093 shares of Upstream Bio Inc worth $132K as of Q2 2026.
  • Diadema Partners sold 2,516 Upstream Bio Inc shares in Q2 2026, an estimated $21.1K.
  • Upstream Bio Inc made up 0.02% of Diadema Partners's portfolio in Q2 2026, its #134 holding.
  • Diadema Partners first reported a position in Upstream Bio Inc in Q4 2025 and has held it in 3 quarters since.
  • Diadema Partners's Upstream Bio Inc position peaked at $557K in Q4 2025.
  • 149 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Diadema Partners's 13F filing for Q2 2026, filed 14 Aug 2026.