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David Shaw’s Praxis Precision Medicines PRAX Stock Holding History

David Shaw’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.72M Buy
+5,140
New +$1.63M ﹤0.01% 3334
2026
Q1 		– Sell
-37,481
Closed -$11.6M – 4948
2025
Q4 		$11M Buy
37,481
+17,685
+89% +$3.29M 0.01% 1662
2025
Q3 		$1.05M Buy
19,796
+740
+4% +$35.9K ﹤0.01% 3423
2025
Q2 		$801K Buy
19,056
+6,848
+56% +$261K ﹤0.01% 3382
2025
Q1 		$462K Sell
12,208
-35,785
-75% -$2.23M ﹤0.01% 3547
2024
Q4 		$3.69M Buy
47,993
+1,629
+4% +$118K ﹤0.01% 2232
2024
Q3 		$2.67M Buy
46,364
+25,287
+120% +$1.37M ﹤0.01% 2466
2024
Q2 		$872K Buy
+21,077
New +$996K ﹤0.01% 3274
2023
Q1 		– Sell
-38,295
Closed -$1.37M – 4773
2022
Q4 		$1.37M Buy
38,295
+19,358
+102% +$604K ﹤0.01% 3224
2022
Q3 		$645K Buy
18,937
+12,475
+193% +$622K ﹤0.01% 3880
2022
Q2 		$237K Buy
+6,462
New +$690K ﹤0.01% 4471
2021
Q3 		– Sell
-3,018
Closed -$827K – 5166
2021
Q2 		$827K Buy
+3,018
New +$1.08M ﹤0.01% 3697

Other funds holding PRAX

JT
Jupiter Topco New York $245B AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $29.1B AUM 60.8% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

David Shaw's PRAX Position: Q2 2026 in Review

David Shaw opened a new position in Praxis Precision Medicines (PRAX) in Q2 2026: 5,140 shares worth $1.72M. The stake represents ﹤0.01% of the portfolio and ranks #3334 among its holdings. This is a return to the name: David Shaw previously reported a position in PRAX as recently as Q4 2025.

David Shaw first reported a position in PRAX in Q2 2021 and has held it in 12 quarters since. The position peaked at $11M in Q4 2025. 307 funds tracked by Wall St. Rank hold PRAX as of Q2 2026.

  • David Shaw held 5,140 shares of Praxis Precision Medicines worth $1.72M as of Q2 2026.
  • Praxis Precision Medicines was a new David Shaw position in Q2 2026.
  • Praxis Precision Medicines made up ﹤0.01% of David Shaw's portfolio in Q2 2026, its #3334 holding.
  • David Shaw first reported a position in Praxis Precision Medicines in Q2 2021 and has held it in 12 quarters since.
  • David Shaw's Praxis Precision Medicines position peaked at $11M in Q4 2025.
  • 307 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.