D.E. Shaw & Co
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D.E. Shaw & Co’s uniQure QURE Stock Holding History

D.E. Shaw & Co’s Portfolio QURE Stock Details QURE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.75M Buy
107,300
+96,100
+858% +$1.95M ﹤0.01% 3016
2025
Q4 		$268K Sell
11,200
-130,000
-92% -$5.02M ﹤0.01% 4202
2025
Q3 		$8.24M Buy
+141,200
New +$2.56M ﹤0.01% 1831
2025
Q2 		– Sell
-16,700
Closed -$177K – 4654
2025
Q1 		$177K Buy
+16,700
New +$234K ﹤0.01% 3949
2021
Q1 		– Sell
-43,900
Closed -$1.59M – 4421
2020
Q4 		$1.59M Hold
43,900
– – ﹤0.01% 2702
2020
Q3 		$1.62M Hold
43,900
– – ﹤0.01% 2539
2020
Q2 		$1.98M Hold
43,900
– – ﹤0.01% 2414
2020
Q1 		$2.08M Hold
43,900
– – ﹤0.01% 2136
2019
Q4 		$3.15M Hold
43,900
– – ﹤0.01% 2112
2019
Q3 		$1.73M Buy
43,900
+20,000
+84% +$1.15M ﹤0.01% 2465
2019
Q2 		$1.87M Buy
+23,900
New +$1.52M ﹤0.01% 2292

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RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
MB
MPM BioImpact Boston, Massachusetts $1.29B AUM 141.72% 1-Year Est. Return