Citadel Advisors’s Upstream Bio, Inc. Common Stock UPB Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2025 Q1	–	Sell	-180,000	Closed	-$2.96M	–	7179
2024 Q4	$2.96M	Buy	+180,000	New	+$2.96M	﹤0.01%	2229