|
1
|
BVF Inc
San Francisco,
California
|
US$3.23億
|
+US$2.03億
|
+5,003,000
|
+193%
|
|
|
2
|
|
US$7213萬
|
-US$20.2萬
|
-4,990
|
-0.3%
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
US$6824萬
|
+US$1227萬
|
+302,558
|
+23%
|
|
|
4
|
Woodline Partners
San Francisco,
California
|
US$4736萬
|
+US$1923萬
|
+474,362
|
+74%
|
|
|
5
|
Newtyn Management
New York
|
US$3014萬
|
+US$2876萬
|
+709,247
|
新
|
|
|
6
|
|
US$2941萬
|
+US$183萬
|
+45,057
|
+7%
|
|
|
7
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
US$2147萬
|
-US$181萬
|
-44,631
|
-8%
|
|
|
8
|
Opaleye Management
Boston,
Massachusetts
|
US$1438萬
|
+US$156萬
|
+38,374
|
+13%
|
|
|
9
|
Geode Capital Management
Boston,
Massachusetts
|
US$1043萬
|
+US$63.1萬
|
+15,555
|
+7%
|
|
|
10
|
Water Island Capital
New York
|
US$1028萬
|
+US$981萬
|
+242,000
|
新
|
|
|
11
|
Alpine Associates Management
Palm Beach,
Florida
|
US$1017萬
|
+US$970萬
|
+239,318
|
新
|
|
|
12
|
State Street
Boston,
Massachusetts
|
US$840萬
|
+US$18.7萬
|
+4,616
|
+2%
|
|
|
13
|
Millennium Management
New York
|
US$834萬
|
-US$34.9萬
|
-8,613
|
-4%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
US$753萬
|
+US$177萬
|
+43,746
|
+33%
|
|
|
15
|
HSBC Holdings
London,
United Kingdom
|
US$631萬
|
+US$606萬
|
+149,523
|
新
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
US$409萬
|
+US$10.9萬
|
+2,689
|
+3%
|
|
|
17
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
US$384萬
|
+US$18.5萬
|
+4,551
|
+5%
|
|
|
18
|
Tudor Investment Corp
Stamford,
Connecticut
|
US$359萬
|
+US$342萬
|
+84,391
|
新
|
|
|
19
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
US$355萬
|
+US$269萬
|
+66,233
|
+381%
|
|
|
20
|
Torno Capital
Cohasset,
Massachusetts
|
US$340萬
|
+US$324萬
|
+80,000
|
新
|
|
|
21
|
Bank of New York Mellon
New York
|
US$320萬
|
+US$1.48萬
|
+364
|
+0.5%
|
|
|
22
|
Verition Fund Management
Greenwich,
Connecticut
|
US$300萬
|
+US$286萬
|
+70,601
|
新
|
|
|
23
|
Vanguard Fiduciary Trust
Malvern,
Pennsylvania
|
US$298萬
|
+US$14.3萬
|
+3,525
|
+5%
|
|
|
24
|
Simcoe Capital
Spokane,
Washington
|
US$289萬
|
–
|
–
|
–
|
|
|
25
|
TLS Advisors
Miami,
Florida
|
US$179萬
|
-US$295萬
|
-72,702
|
-63%
|
|
