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Zymeworks
ZYME

115 hedge funds and large institutions have $512M invested in Zymeworks in 2023 Q1 according to their latest regulatory filings, with 40 funds opening new positions, 36 increasing their positions, 27 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 20

72% more call options, than puts

Call options by funds: $2.46M | Put options by funds: $1.43M

33% more repeat investments, than reductions

Existing positions increased: 36 | Existing positions reduced: 27

20% more funds holding

Funds holding: 96 → 115 (+19)

14% more capital invested

Capital invested by funds: $450M → $512M (+$62.5M)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

2.31% less ownership

Funds ownership: 90.84% → 88.53% (-2.3%)

Holders
115
Holders Change
+19
Holders Change %
+19.79%
% of All Funds
1.83%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
40
Increased
36
Reduced
27
Closed
20
Calls
$2.46M
Puts
$1.43M
Net Calls
+$1.02M
Net Calls Change
+$998K

Top Buyers

Rank Fund Capital Flow
1
EC
EcoR1 Capital
California
+$22M
2
TCM
Tang Capital Management
California
+$6.1M
3
Millennium Management
Millennium Management
New York
+$4.65M
4
FCM
Farallon Capital Management
California
+$4.36M
5
HF
HRT Financial
New York
+$2.85M

Top Sellers

Rank Fund Capital Flow
1
BBA
Baker Bros. Advisors
New York
-$13.4M
2
PA
Perceptive Advisors
New York
-$9.88M
3
BC
Brookfield Corp
Ontario, Canada
-$5.83M
4
SC
Sessa Capital
New York
-$5.82M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
-$4.81M
Name Holding Trade Value Shares
Change 		Change in
Stake
PMAM
26
Picton Mahoney Asset Management
Ontario, Canada
$2.87M +$510K +58,516 +23%
UOC
27
UBS O'Connor
Illinois
$2.75M +$2.65M +303,732 New
CSS
28
Cubist Systematic Strategies
Connecticut
$2.67M +$2.1M +241,177 +441%
Voloridge Investment Management
29
Voloridge Investment Management
Florida
$2.29M +$1.84M +211,383 +505%
Point72 Asset Management
30
Point72 Asset Management
Connecticut
$1.79M -$4.81M -551,350 -74%
6CM
31
683 Capital Management
New York
$1.72M -$872K -100,000 -34%
Royal Bank of Canada
32
Royal Bank of Canada
Ontario, Canada
$1.55M +$25.8K +2,962 +2%
Qube Research & Technologies (QRT)
33
Qube Research & Technologies (QRT)
United Kingdom
$1.55M +$1.49M +171,314 New
State Street
34
State Street
Massachusetts
$1.38M +$445K +51,032 +50%
Victory Capital Management
35
Victory Capital Management
Texas
$1.37M +$1.33M +151,950 New
Jane Street
36
Jane Street
New York
$1.27M +$1.23M +140,816 New
Swiss National Bank
37
Swiss National Bank
Switzerland
$1.17M +$1.13M +129,200 New
CANY
38
Caxton Associates (New York)
New York
$1.09M +$14.2K +1,633 +1%
NGM
39
North Growth Management
British Columbia, Canada
$1.09M +$392K +45,000 +60%
Bank of America
40
Bank of America
North Carolina
$980K +$700K +80,248 +286%
JF
41
Jump Financial
Illinois
$862K +$553K +63,424 +199%
RJA
42
Raymond James & Associates
Florida
$843K -$531K -60,917 -40%
Dimensional Fund Advisors
43
Dimensional Fund Advisors
Texas
$812K +$783K +89,793 New
Wells Fargo
44
Wells Fargo
California
$767K -$144K -16,466 -16%
Renaissance Technologies
45
Renaissance Technologies
New York
$754K -$319K -36,600 -31%
VRS
46
Virginia Retirement Systems
Virginia
$738K +$712K +81,600 New
Squarepoint
47
Squarepoint
New York
$710K +$685K +78,504 New
KCM
48
Kennedy Capital Management
Missouri
$709K +$453 +52 +0.1%
Citigroup
49
Citigroup
New York
$682K +$432K +49,593 +192%
Verition Fund Management
50
Verition Fund Management
Connecticut
$555K +$535K +61,386 New
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ZYME Hedge Fund Activity: Q1 2023 in Review

115 of the 6,275 institutional investors tracked by Wall St. Rank reported a position in Zymeworks (ZYME) for Q1 2023, worth a combined $512M — up 14% from $450M a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new ZYME positions and 20 closed out — a net gain of 20 holders — while 36 added to existing stakes and 27 trimmed.

The largest buyer was EcoR1 Capital, adding an estimated $22M. The largest seller was Baker Bros. Advisors, exiting entirely with an estimated $13.4M sold.

  • 115 institutional investors held Zymeworks (ZYME) as of Q1 2023, up from 96 in Q4 2022.
  • Funds reported $512M of Zymeworks stock for Q1 2023, up 14% quarter-over-quarter.
  • 40 funds opened new Zymeworks positions in Q1 2023 and 20 closed out, a net change of +20 holders.
  • The largest Zymeworks buyer in Q1 2023 was EcoR1 Capital, an estimated $22M added.
  • The largest Zymeworks seller in Q1 2023 was Baker Bros. Advisors, an estimated $13.4M sold.

Based on aggregated 13F filings for Q1 2023.