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Xenon Pharmaceuticals
XENE

Overview Fund Activity

203 hedge funds and large institutions have $2.59B invested in Xenon Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 40 funds opening new positions, 77 increasing their positions, 54 reducing their positions, and 39 closing their positions.

Holders
203
Holders Change
-3
Holders Change %
-1.46%
% of All Funds
2.73%
Holding in Top 10
10
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-28.57%
% of All Funds
0.13%
New
40
Increased
77
Reduced
54
Closed
39
Calls
$8.93M
Puts
$7.08M
Net Calls
+$1.85M
Net Calls Change
-$6.04M

Top Buyers

1
BlackRock
1
BlackRock
New York
$168M
2
Holocene Advisors
2
Holocene Advisors
New York
$56.6M
3
State Street
3
State Street
Massachusetts
$43.2M
4
Geode Capital Management
4
Geode Capital Management
Massachusetts
$30.4M
5
B
5
Braidwell
Connecticut
$113M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$68.1M
2
Capital World Investors
2
Capital World Investors
California
$20.5M
3
SC
3
Samlyn Capital
New York
$0
4
T. Rowe Price Investment Management
4
T. Rowe Price Investment Management
Maryland
$2.41M
5
LGM
5
Logos Global Management
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
DCM
51
DAFNA Capital Management
California
$9.01M 287,939 +14,200 +5%
ACM
52
ADAR1 Capital Management
Texas
$8.12M 259,503 +131,955 +103%
GIM
53
Granahan Investment Management
Massachusetts
$7.51M 240,038 +56,230 +31%
DnB Asset Management
54
DnB Asset Management
Norway
$7.33M 234,157 +4,675 +2%
Federated Hermes
55
Federated Hermes
Pennsylvania
$7.28M 232,500 – –
NL
56
Nuveen LLC
North Carolina
$7.15M 228,567 +228,567 New
PA
57
Perceptive Advisors
New York
$6.28M 200,791 -124,533 -38%
GPP
58
Great Point Partners
Connecticut
$6.26M 200,000 -45,272 -18%
Charles Schwab
59
Charles Schwab
California
$6.02M 192,242 +192,242 New
FLAM
60
First Light Asset Management
Minnesota
$5.9M 188,367 -439,537 -70%
Axa
61
Axa
France
$5.5M 175,632 +282 +0.2%
State of Wisconsin Investment Board
62
State of Wisconsin Investment Board
Wisconsin
$5.47M 174,850 +77,701 +80%
New York State Common Retirement Fund
63
New York State Common Retirement Fund
New York
$5.21M 166,472 +24,100 +17%
FCMV
64
Foresite Capital Management VI
California
$5.01M 160,000 +160,000 New
FCMI
65
Foresite Capital Management IV
California
$5.01M 160,000 +160,000 New
NFT
66
Nan Fung Trinity
Hong Kong
$4.96M 158,605 +158,605 New
UBS Group
67
UBS Group
Switzerland
$4.79M 153,058 +47,725 +45%
Barclays
68
Barclays
United Kingdom
$4.78M 152,770 +133,500 +693%
PHP
69
Parkman Healthcare Partners
Connecticut
$4.71M 150,373 -24,203 -14%
Neuberger Berman Group
70
Neuberger Berman Group
New York
$4.61M 147,411 +102,559 +229%
Royal Bank of Canada
71
Royal Bank of Canada
Ontario, Canada
$4.61M 147,226 +87,860 +148%
D.E. Shaw & Co
72
D.E. Shaw & Co
New York
$4.44M 141,783 -10,405 -7%
Swiss National Bank
73
Swiss National Bank
Switzerland
$3.89M 124,300 -1,300 -1%
Ameriprise
74
Ameriprise
Minnesota
$3.82M 122,026 +18,402 +18%
Citadel Advisors
75
Citadel Advisors
Florida
$3.76M 120,045 -567,043 -83%
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