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Xenon Pharmaceuticals

246 hedge funds and large institutions have $3.78B invested in Xenon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 81 increasing their positions, 74 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more capital invested

Capital invested by funds: $ → $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0% more funds holding in top 10

Funds holding in top 10: 99 (0)

0.06% less ownership

Funds ownership: 109.36%109.29% (-0.06%)

34% less call options, than puts

Call options by funds: $36.4M | Put options by funds: $54.7M

Holders
246
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
9
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$36.4M
Puts
$54.7M
Net Calls
Net Calls Change

Top Buyers

1 +$48.5M
2 +$34.5M
3 +$20.6M
4
Federated Hermes
Federated Hermes
Pennsylvania
+$18.5M
5
Two Sigma Investments
Two Sigma Investments
New York
+$18.3M

Top Sellers

1 -$74.8M
2 -$37.8M
3 -$35M
4
Millennium Management
Millennium Management
New York
-$31.5M
5
Holocene Advisors
Holocene Advisors
New York
-$29.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Lazard Asset Management
101
Lazard Asset Management
New York
$3.53M
YIH
102
Y-Intercept (HK)
Hong Kong
$3.27M
Legal & General Group
103
Legal & General Group
United Kingdom
$3.15M
AA
104
ALPS Advisors
Colorado
$2.84M
VOYA Investment Management
105
VOYA Investment Management
Georgia
$2.73M
SI
106
Sofinnova Investments
California
$2.68M
California State Teachers Retirement System (CalSTRS)
107
California State Teachers Retirement System (CalSTRS)
California
$2.54M
UBS Group
108
UBS Group
Switzerland
$2.35M
Invesco
109
Invesco
Georgia
$2.28M
EAM
110
Erste Asset Management
Austria
$2.22M
NAMI
111
Nomura Asset Management International
Pennsylvania
$2.15M
SEI Investments
112
SEI Investments
Pennsylvania
$1.97M
MIM
113
MetLife Investment Management
New Jersey
$1.88M
DekaBank Deutsche Girozentrale
114
DekaBank Deutsche Girozentrale
Germany
$1.82M
AGP
115
Artia Global Partners
Florida
$1.79M
TD Asset Management
116
TD Asset Management
Ontario, Canada
$1.71M
LCM
117
Legato Capital Management
California
$1.66M
Envestnet Asset Management
118
Envestnet Asset Management
Illinois
$1.6M
BFM
119
Boothbay Fund Management
New York
$1.6M
Mirae Asset Global ETFs Holdings
120
Mirae Asset Global ETFs Holdings
Hong Kong
$1.58M
DFCM
121
Dark Forest Capital Management
Puerto Rico
$1.5M
Manulife (Manufacturers Life Insurance)
122
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.45M
JF
123
Jump Financial
Illinois
$1.39M
D.E. Shaw & Co
124
D.E. Shaw & Co
New York
$1.38M
BAMCO Inc
125
BAMCO Inc
New York
$1.34M