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Xenon Pharmaceuticals

246 hedge funds and large institutions have $3.78B invested in Xenon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 81 increasing their positions, 74 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more capital invested

Capital invested by funds: $ → $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0% more funds holding in top 10

Funds holding in top 10: 99 (0)

0.06% less ownership

Funds ownership: 109.36%109.29% (-0.06%)

34% less call options, than puts

Call options by funds: $36.4M | Put options by funds: $54.7M

Holders
246
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
9
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$36.4M
Puts
$54.7M
Net Calls
Net Calls Change

Top Buyers

1 +$48.5M
2 +$34.5M
3 +$20.6M
4
Federated Hermes
Federated Hermes
Pennsylvania
+$18.5M
5
Two Sigma Investments
Two Sigma Investments
New York
+$18.3M

Top Sellers

1 -$74.8M
2 -$37.8M
3 -$35M
4
Millennium Management
Millennium Management
New York
-$31.5M
5
Holocene Advisors
Holocene Advisors
New York
-$29.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Handelsbanken Fonder
126
Handelsbanken Fonder
Sweden
$1.34M
IIM
127
INTECH Investment Management
Florida
$1.16M
Zurich Cantonal Bank
128
Zurich Cantonal Bank
Switzerland
$1.15M
LIP
129
Lighthouse Investment Partners
Florida
$1.12M
QCM
130
Quantinno Capital Management
New York
$1.1M
RG
131
Rathbones Group
United Kingdom
$1.06M
CCM
132
Cinctive Capital Management
New York
$1.05M
HWM
133
HighMark Wealth Management
Minnesota
$1.03M
VAS
134
Vestmark Advisory Solutions
Massachusetts
$981K
XT
135
XTX Topco
Cayman Islands
$964K
AssetMark Inc
136
AssetMark Inc
California
$953K
BC
137
Birchview Capital
Vermont
$941K
PFSRSONJ
138
Police & Firemen's Retirement System of New Jersey
New Jersey
$902K
State of New Jersey Common Pension Fund D
139
State of New Jersey Common Pension Fund D
New Jersey
$885K
Walleye Capital
140
Walleye Capital
New York
$878K
Creative Planning
141
Creative Planning
Kansas
$861K
Stifel Financial
142
Stifel Financial
Missouri
$787K
ProShare Advisors
143
ProShare Advisors
Maryland
$774K
ET
144
Entropy Technologies
New York
$763K
ASRS
145
Arizona State Retirement System
Arizona
$725K
CCIA
146
Campbell & Co Investment Adviser
Maryland
$722K
BCI
147
Brinker Capital Investments
Pennsylvania
$646K
SOAM
148
SBI Okasan Asset Management
Japan
$638K
JSSH
149
J. Safra Sarasin Holding
$609K
CIBC World Market
150
CIBC World Market
Ontario, Canada
$603K