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Xenon Pharmaceuticals

290 hedge funds and large institutions have $5.8B invested in Xenon Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 81 funds opening new positions, 124 increasing their positions, 60 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

145% more first-time investments, than exits

New positions opened: 81 | Existing positions closed: 33

107% more repeat investments, than reductions

Existing positions increased: 124 | Existing positions reduced: 60

53% more capital invested

Capital invested by funds: $3.78B → $5.8B (+$2.02B)

33% more funds holding in top 10

Funds holding in top 10: 912 (+3)

18% more funds holding

Funds holding: 246290 (+44)

11.18% more ownership

Funds ownership: 109.29%120.48% (+11%)

8% less call options, than puts

Call options by funds: $127M | Put options by funds: $138M

Holders
290
Holders Change
+44
Holders Change %
+17.89%
% of All Funds
3.57%
Holding in Top 10
12
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+33.33%
% of All Funds
0.15%
New
81
Increased
124
Reduced
60
Closed
33
Calls
$127M
Puts
$138M
Net Calls
-$11M
Net Calls Change
+$7.38M
Name Holding Trade Value Shares
Change
Change in
Stake
O
26
OrbiMed
New York
$61.6M +$28.2M +612,771 +137%
Federated Hermes
27
Federated Hermes
Pennsylvania
$56.5M +$13.8M +300,000 +45%
T. Rowe Price Investment Management
28
T. Rowe Price Investment Management
Maryland
$55.4M +$18.6M +404,342 +74%
Capital World Investors
29
Capital World Investors
California
$48.9M +$8.49M +184,335 +28%
CC
30
Commodore Capital
New York
$48M -$44.9M -975,000 -54%
FTM
31
First Turn Management
California
$45.8M -$594K -12,899 -2%
Goldman Sachs
32
Goldman Sachs
New York
$44.8M +$3.4M +73,828 +11%
RSCM
33
Rock Springs Capital Management
Maryland
$44.4M -$1.14M -24,768 -3%
Fiera Capital (Canada)
34
Fiera Capital (Canada)
Quebec, Canada
$41.3M +$1.08M +23,473 +3%
American Century Companies
35
American Century Companies
Missouri
$39.5M -$53.4K -1,159 -0.2%
Pictet Asset Management
36
Pictet Asset Management
Switzerland
$39.2M +$2.48M +53,724 +9%
VPC
37
Vestal Point Capital
New York
$37.2M +$1.84M +39,900 +7%
Aberdeen Group
38
Aberdeen Group
United Kingdom
$35.5M -$6.47M -140,362 -19%
Two Sigma Investments
39
Two Sigma Investments
New York
$35.2M +$7.8M +169,342 +39%
MB
40
MPM BioImpact
Massachusetts
$34.2M +$4.75M +103,086 +21%
Loomis, Sayles & Company
41
Loomis, Sayles & Company
Massachusetts
$32.8M -$2.17M -47,135 -8%
VPM
42
Vanguard Portfolio Management
Pennsylvania
$31.6M +$25M +543,062 New
Northern Trust
43
Northern Trust
Illinois
$30.7M +$4.1M +89,069 +20%
PHP
44
Parkman Healthcare Partners
Connecticut
$28.9M +$15.8M +342,851 +222%
Tudor Investment Corp
45
Tudor Investment Corp
Connecticut
$28.8M +$11.1M +241,589 +95%
OCA
46
Octagon Capital Advisors
New York
$28.5M +$22.6M +490,000 New
NHAS
47
Novo Holdings A/S
Denmark
$28.2M +$22.4M +485,438 New
CS
48
Candriam SCA
Luxembourg
$27.7M +$2.72M +59,092 +14%
Morgan Stanley
49
Morgan Stanley
New York
$27.5M +$8.27M +179,427 +61%
Adage Capital Partners
50
Adage Capital Partners
Massachusetts
$27.3M -$9.91M -215,100 -31%