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Wave Life Sciences

196 hedge funds and large institutions have $1.06B invested in Wave Life Sciences in 2025 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 83 increasing their positions, 52 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

164% more call options, than puts

Call options by funds: $4.91M | Put options by funds: $1.86M

65% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 20

60% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 52

7% more funds holding

Funds holding: 183196 (+13)

1.28% more ownership

Funds ownership: 84.33%85.6% (+1.3%)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

33% less capital invested

Capital invested by funds: $1.59B → $1.06B (-$529M)

Holders
196
Holders Change
+13
Holders Change %
+7.1%
% of All Funds
2.63%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
33
Increased
83
Reduced
52
Closed
20
Calls
$4.91M
Puts
$1.86M
Net Calls
+$3.05M
Net Calls Change
-$854K
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$147M
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$101M +$31.7M +2,894,396 +30%
BlackRock
3
BlackRock
New York
$77.8M +$2.94M +268,449 +3%
MC
4
Maverick Capital
Texas
$66.8M +$4.82K +441 +0%
DCM
5
Driehaus Capital Management
Illinois
$51.4M -$3.87M -353,850 -5%
MCM
6
M28 Capital Management
Connecticut
$45.8M
KCM
7
Kynam Capital Management
New Jersey
$39.6M
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$33.3M -$10.6M -973,575 -19%
BG
9
Bellevue Group
Switzerland
$33.1M
6CM
10
683 Capital Management
New York
$31.7M +$1.53M +140,000 +4%
SL
11
Siren LLC
Connecticut
$29.9M -$592K -54,169 -1%
Vanguard Group
12
Vanguard Group
Pennsylvania
$25.9M +$261K +23,891 +0.8%
EA
13
Emerald Advisers
Pennsylvania
$25.3M -$315K -28,811 -0.9%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$21M +$1.33M +121,648 +5%
Primecap Management
15
Primecap Management
California
$20.3M -$131K -12,000 -0.5%
Loomis, Sayles & Company
16
Loomis, Sayles & Company
Massachusetts
$19.7M +$8.48M +775,674 +47%
State Street
17
State Street
Massachusetts
$19.5M -$94.4K -8,634 -0.4%
Artisan Partners
18
Artisan Partners
Wisconsin
$19.2M +$5.07M +463,363 +24%
Fidelity Investments
19
Fidelity Investments
Massachusetts
$17.3M +$3.47M +317,107 +17%
EMFAT
20
Emerald Mutual Fund Advisers Trust
Pennsylvania
$15.6M -$2.34K -214 -0%
P
21
Pfizer
New York
$15.2M
AAA
22
Affinity Asset Advisors
New York
$14.7M +$3.55M +325,000 +22%
MB
23
MPM BioImpact
Massachusetts
$12.2M +$222K +20,343 +1%
Morgan Stanley
24
Morgan Stanley
New York
$9.53M +$1.33M +121,541 +11%
JP Morgan Chase
25
JP Morgan Chase
New York
$9.53M +$5.19M +474,600 +67%

WVE Hedge Fund Activity: Q1 2025 in Review

196 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q1 2025, worth a combined $1.06B — down 33% from $1.59B a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new WVE positions and 20 closed out — a net gain of 13 holders — while 83 added to existing stakes and 52 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $31.7M. The largest seller was Millennium Management, cutting an estimated $12.6M.

  • 196 institutional investors held Wave Life Sciences (WVE) as of Q1 2025, up from 183 in Q4 2024.
  • Funds reported $1.06B of Wave Life Sciences stock for Q1 2025, down 33% quarter-over-quarter.
  • 33 funds opened new Wave Life Sciences positions in Q1 2025 and 20 closed out, a net change of +13 holders.
  • The largest Wave Life Sciences buyer in Q1 2025 was Adage Capital Partners, an estimated $31.7M added.
  • The largest Wave Life Sciences seller in Q1 2025 was Millennium Management, an estimated $12.6M sold.

Based on aggregated 13F filings for Q1 2025.