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Wave Life Sciences

176 hedge funds and large institutions have $903M invested in Wave Life Sciences in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 84 increasing their positions, 39 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,001% more call options, than puts

Call options by funds: $3.37M | Put options by funds: $306K

115% more repeat investments, than reductions

Existing positions increased: 84 | Existing positions reduced: 39

3.71% more ownership

Funds ownership: 85.6%89.31% (+3.7%)

10% less funds holding

Funds holding: 196176 (-20)

15% less capital invested

Capital invested by funds: $1.06B → $903M (-$159M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

43% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 40

Holders
176
Holders Change
-20
Holders Change %
-10.2%
% of All Funds
2.32%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
23
Increased
84
Reduced
39
Closed
40
Calls
$3.37M
Puts
$306K
Net Calls
+$3.06M
Net Calls Change
+$13K
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$118M
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$97.6M +$16.5M +2,500,000 +20%
BlackRock
3
BlackRock
New York
$67.5M +$4.99M +755,104 +8%
MC
4
Maverick Capital
Texas
$53.7M
DCM
5
Driehaus Capital Management
Illinois
$42.5M +$1.14M +172,920 +3%
MCM
6
M28 Capital Management
Connecticut
$36.8M
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$33.7M +$7.03M +1,065,112 +26%
KCM
8
Kynam Capital Management
New Jersey
$29.6M -$2.24M -339,444 -7%
6CM
9
683 Capital Management
New York
$26.7M +$1.16M +175,000 +4%
BG
10
Bellevue Group
Switzerland
$26.6M
SL
11
Siren LLC
Connecticut
$24M
Vanguard Group
12
Vanguard Group
Pennsylvania
$22.6M +$1.79M +270,674 +8%
Loomis, Sayles & Company
13
Loomis, Sayles & Company
Massachusetts
$21.4M +$5.67M +859,160 +35%
EA
14
Emerald Advisers
Pennsylvania
$21.2M +$816K +123,561 +4%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$17.9M +$1.1M +166,982 +6%
State Street
16
State Street
Massachusetts
$17.9M +$2.24M +338,792 +14%
Primecap Management
17
Primecap Management
California
$16M -$275K -41,670 -2%
Artisan Partners
18
Artisan Partners
Wisconsin
$14.7M -$695K -105,318 -4%
AAA
19
Affinity Asset Advisors
New York
$13M +$1.16M +175,308 +10%
EMFAT
20
Emerald Mutual Fund Advisers Trust
Pennsylvania
$12.6M +$44K +6,669 +0.3%
P
21
Pfizer
New York
$12.2M
JP Morgan Chase
22
JP Morgan Chase
New York
$10.2M +$2.58M +390,078 +33%
Morgan Stanley
23
Morgan Stanley
New York
$10M +$2.4M +364,111 +31%
MB
24
MPM BioImpact
Massachusetts
$9.78M -$28.5K -4,318 -0.3%
Charles Schwab
25
Charles Schwab
California
$6.57M +$314K +47,533 +5%

WVE Hedge Fund Activity: Q2 2025 in Review

176 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q2 2025, worth a combined $903M — down 15% from $1.06B a quarter earlier.

Sellers outnumbered buyers: 40 funds closed out of WVE and 23 opened new positions — a net loss of 17 holders — while 39 trimmed existing stakes and 84 added.

The largest buyer was Adage Capital Partners, adding an estimated $16.5M. The largest seller was Fidelity Investments, cutting an estimated $10.1M.

  • 176 institutional investors held Wave Life Sciences (WVE) as of Q2 2025, down from 196 in Q1 2025.
  • Funds reported $903M of Wave Life Sciences stock for Q2 2025, down 15% quarter-over-quarter.
  • 23 funds opened new Wave Life Sciences positions in Q2 2025 and 40 closed out, a net change of -17 holders.
  • The largest Wave Life Sciences buyer in Q2 2025 was Adage Capital Partners, an estimated $16.5M added.
  • The largest Wave Life Sciences seller in Q2 2025 was Fidelity Investments, an estimated $10.1M sold.

Based on aggregated 13F filings for Q2 2025.