Wave Life Sciences
WVE
232 hedge funds and large institutions have $1.25B invested in Wave Life Sciences in 2026 Q1 according to their latest regulatory filings, with 52 funds opening new positions, 107 increasing their positions, 47 reducing their positions, and 35 closing their positions.
193% more call options, than puts
Call options by funds: $29.1M | Put options by funds: $9.95M
128% more repeat investments, than reductions
Existing positions increased: 107 | Existing positions reduced: 47
49% more first-time investments, than exits
New positions opened: 52 | Existing positions closed: 35
6% more funds holding
Funds holding: 218 → 232 (+14)
17.57% less ownership
Funds ownership: 109.27% → 91.71% (-18%)
25% less funds holding in top 10
Funds holding in top 10: 8 → 6 (-2)
60% less capital invested
Capital invested by funds: $3.11B → $1.25B (-$1.86B)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
+$114M |
| 2 |
Marshall Wace
London,
United Kingdom
|
+$23.3M |
| 3 |
BlackRock
New York
|
+$19.1M |
| 4 |
Citadel Advisors
Miami,
Florida
|
+$18.4M |
| 5 |
T. Rowe Price Associates
Baltimore,
Maryland
|
+$16.9M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
-$130M |
| 2 |
DGM
Darwin Global Management
St. Helier,
Jersey
|
-$125M |
| 3 |
Adage Capital Partners
Boston,
Massachusetts
|
-$114M |
| 4 |
Loomis, Sayles & Company
Boston,
Massachusetts
|
-$34.7M |
| 5 |
BG
Bellevue Group
Kuesnacht,
Switzerland
|
-$19.3M |
WVE Hedge Fund Activity: Q1 2026 in Review
232 of the 8,187 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q1 2026, worth a combined $1.25B — down 60% from $3.11B a quarter earlier.
Buyers outnumbered sellers: 52 funds opened new WVE positions and 35 closed out — a net gain of 17 holders — while 107 added to existing stakes and 47 trimmed.
The largest buyer was RA Capital Management, adding an estimated $114M. The largest seller was Fidelity Investments, cutting an estimated $130M.
- 232 institutional investors held Wave Life Sciences (WVE) as of Q1 2026, up from 218 in Q4 2025.
- Funds reported $1.25B of Wave Life Sciences stock for Q1 2026, down 60% quarter-over-quarter.
- 52 funds opened new Wave Life Sciences positions in Q1 2026 and 35 closed out, a net change of +17 holders.
- The largest Wave Life Sciences buyer in Q1 2026 was RA Capital Management, an estimated $114M added.
- The largest Wave Life Sciences seller in Q1 2026 was Fidelity Investments, an estimated $130M sold.
Based on aggregated 13F filings for Q1 2026.