We are live on ! Find out more
WVE icon

Wave Life Sciences

189 hedge funds and large institutions have $1.05B invested in Wave Life Sciences in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 62 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

101% more call options, than puts

Call options by funds: $9.64M | Put options by funds: $4.79M

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

16% more capital invested

Capital invested by funds: $903M → $1.05B (+$148M)

7% more funds holding

Funds holding: 176189 (+13)

0.97% more ownership

Funds ownership: 89.31%90.29% (+0.97%)

2% less repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 62

Holders
189
Holders Change
+13
Holders Change %
+7.39%
% of All Funds
2.48%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
32
Increased
61
Reduced
62
Closed
18
Calls
$9.64M
Puts
$4.79M
Net Calls
+$4.85M
Net Calls Change
+$1.79M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$133M
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$107M -$3.63M -448,716 -3%
BlackRock
3
BlackRock
New York
$76.4M +$381K +47,097 +0.5%
MC
4
Maverick Capital
Texas
$61.4M +$1.05M +130,173 +2%
DCM
5
Driehaus Capital Management
Illinois
$46.1M -$1.89M -233,459 -4%
MCM
6
M28 Capital Management
Connecticut
$41.5M
Fidelity Investments
7
Fidelity Investments
Massachusetts
$37.6M +$36.5M +4,511,237 +729%
KCM
8
Kynam Capital Management
New Jersey
$33.4M
6CM
9
683 Capital Management
New York
$30.4M +$405K +50,000 +1%
BG
10
Bellevue Group
Switzerland
$30M
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$29.6M -$9.27M -1,145,911 -22%
Federated Hermes
12
Federated Hermes
Pennsylvania
$27.5M +$30.3M +3,750,140 +678,145%
SL
13
Siren LLC
Connecticut
$27.1M
Vanguard Group
14
Vanguard Group
Pennsylvania
$23M -$2.73M -337,241 -10%
EA
15
Emerald Advisers
Pennsylvania
$21.9M -$2.11M -260,219 -8%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$21.4M +$1.29M +158,989 +6%
Loomis, Sayles & Company
17
Loomis, Sayles & Company
Massachusetts
$21.3M -$3.16M -390,234 -12%
State Street
18
State Street
Massachusetts
$20.8M +$725K +89,611 +3%
Goldman Sachs
19
Goldman Sachs
New York
$15.6M +$9.05M +1,118,056 +111%
SC
20
Stempoint Capital
New York
$15.4M +$9.79M +1,209,814 +134%
AAA
21
Affinity Asset Advisors
New York
$15.4M +$807K +99,692 +5%
Primecap Management
22
Primecap Management
California
$13.9M -$4.59M -567,200 -23%
P
23
Pfizer
New York
$13.7M
EMFAT
24
Emerald Mutual Fund Advisers Trust
Pennsylvania
$12.9M -$1.39M -171,427 -9%
MB
25
MPM BioImpact
Massachusetts
$11M

WVE Hedge Fund Activity: Q3 2025 in Review

189 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q3 2025, worth a combined $1.05B — up 16% from $903M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new WVE positions and 18 closed out — a net gain of 14 holders — while 61 added to existing stakes and 62 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $36.5M. The largest seller was T. Rowe Price Associates, cutting an estimated $9.27M.

  • 189 institutional investors held Wave Life Sciences (WVE) as of Q3 2025, up from 176 in Q2 2025.
  • Funds reported $1.05B of Wave Life Sciences stock for Q3 2025, up 16% quarter-over-quarter.
  • 32 funds opened new Wave Life Sciences positions in Q3 2025 and 18 closed out, a net change of +14 holders.
  • The largest Wave Life Sciences buyer in Q3 2025 was Fidelity Investments, an estimated $36.5M added.
  • The largest Wave Life Sciences seller in Q3 2025 was T. Rowe Price Associates, an estimated $9.27M sold.

Based on aggregated 13F filings for Q3 2025.