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Wave Life Sciences

218 hedge funds and large institutions have $3.11B invested in Wave Life Sciences in 2025 Q4 according to their latest regulatory filings, with 73 funds opening new positions, 78 increasing their positions, 47 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

195% more capital invested

Capital invested by funds: $1.05B → $3.11B (+$2.06B)

100% more funds holding in top 10

Funds holding in top 10: 48 (+4)

87% more first-time investments, than exits

New positions opened: 73 | Existing positions closed: 39

66% more repeat investments, than reductions

Existing positions increased: 78 | Existing positions reduced: 47

18.99% more ownership

Funds ownership: 90.29%109.27% (+19%)

16% more call options, than puts

Call options by funds: $50M | Put options by funds: $42.9M

15% more funds holding

Funds holding: 189218 (+29)

Holders
218
Holders Change
+29
Holders Change %
+15.34%
% of All Funds
2.65%
Holding in Top 10
8
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+100%
% of All Funds
0.1%
New
73
Increased
78
Reduced
47
Closed
39
Calls
$50M
Puts
$42.9M
Net Calls
+$7.04M
Net Calls Change
+$2.19M
Name Holding Trade Value Shares
Change
Change in
Stake
GP
1
GSK plc
$310M +$185M +18,245,691 New
RCM
2
RA Capital Management
Massachusetts
$309M +$10.2K +1,000 +0%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$257M +$102M +10,005,609 +195%
BlackRock
4
BlackRock
New York
$215M +$22.5M +2,218,094 +21%
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$166M -$48.6M -4,781,723 -33%
MC
6
Maverick Capital
Texas
$158M +$9.03M +888,381 +11%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$126M +$34.2M +3,362,880 +83%
DGM
8
Darwin Global Management
Jersey
$125M +$74.2M +7,298,421 New
DCM
9
Driehaus Capital Management
Illinois
$112M +$2.88M +283,007 +4%
MCM
10
M28 Capital Management
Connecticut
$96.3M
Federated Hermes
11
Federated Hermes
Pennsylvania
$80.7M +$10.1M +993,827 +26%
Primecap Management
12
Primecap Management
California
$69.6M +$22.3M +2,196,632 +116%
6CM
13
683 Capital Management
New York
$68.3M -$1.37M -135,000 -3%
Vanguard Group
14
Vanguard Group
Pennsylvania
$60.8M +$4.41M +433,910 +14%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$53.9M +$2.56M +251,740 +9%
State Street
16
State Street
Massachusetts
$50.9M +$1.52M +149,718 +5%
Goldman Sachs
17
Goldman Sachs
New York
$48.5M +$7.41M +728,945 +34%
AAA
18
Affinity Asset Advisors
New York
$45.9M +$6.1M +600,000 +29%
EA
19
Emerald Advisers
Pennsylvania
$41.7M -$5.51M -541,811 -18%
SL
20
Siren LLC
Connecticut
$41.6M -$12.7M -1,246,322 -34%
KCM
21
Kynam Capital Management
New Jersey
$36.9M -$24.3M -2,390,948 -52%
Loomis, Sayles & Company
22
Loomis, Sayles & Company
Massachusetts
$34.7M -$8.79M -865,243 -30%
P
23
Pfizer
New York
$31.9M
FLAM
24
First Light Asset Management
Minnesota
$31.5M +$18.8M +1,853,851 New
BG
25
Bellevue Group
Switzerland
$25.3M -$26.5M -2,603,940 -64%