D.E. Shaw & Co
WVE icon

D.E. Shaw & Co’s Wave Life Sciences WVE Stock Holding History

D.E. Shaw & Co’s Portfolio WVE Stock Details WVE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$524K Sell
72,305
-193,827
-73% -$2.53M ﹤0.01% 3831
2025
Q4 		$4.52M Buy
+266,132
New +$2.7M ﹤0.01% 2389
2025
Q3 		– Sell
-271,474
Closed -$1.76M – 4974
2025
Q2 		$1.76M Buy
271,474
+164,920
+155% +$1.09M ﹤0.01% 2832
2025
Q1 		$861K Sell
106,554
-609,699
-85% -$6.67M ﹤0.01% 3180
2024
Q4 		$8.86M Buy
716,253
+297,792
+71% +$3.97M 0.01% 1582
2024
Q3 		$3.43M Buy
418,461
+309,894
+285% +$1.85M ﹤0.01% 2261
2024
Q2 		$542K Sell
108,567
-176,525
-62% -$1.01M ﹤0.01% 3577
2024
Q1 		$1.76M Buy
+285,092
New +$1.43M ﹤0.01% 2731
2022
Q4 		– Sell
-307,175
Closed -$1.11M – 5163
2022
Q3 		$1.11M Sell
307,175
-633,290
-67% -$2.1M ﹤0.01% 3518
2022
Q2 		$3.06M Sell
940,465
-150,835
-14% -$290K ﹤0.01% 2692
2022
Q1 		$2.18M Sell
1,091,300
-18,989
-2% -$46.5K ﹤0.01% 3203
2021
Q4 		$3.49M Buy
1,110,289
+8,639
+0.8% +$35.9K ﹤0.01% 2789
2021
Q3 		$5.4M Sell
1,101,650
-153,910
-12% -$933K ﹤0.01% 2045
2021
Q2 		$8.36M Sell
1,255,560
-6,549
-0.5% -$42.8K 0.01% 1647
2021
Q1 		$7.08M Sell
1,262,109
-237,150
-16% -$2.28M 0.01% 1606
2020
Q4 		$11.8M Buy
1,499,259
+792,844
+112% +$6.65M 0.01% 1286
2020
Q3 		$6M Buy
706,415
+144,454
+26% +$1.58M 0.01% 1570
2020
Q2 		$5.85M Buy
561,961
+529,849
+1,650% +$4.99M 0.01% 1554
2020
Q1 		$301K Buy
32,112
+9,564
+42% +$81.5K ﹤0.01% 3466
2019
Q4 		$181K Buy
22,548
+3,858
+21% +$94.6K ﹤0.01% 3821
2019
Q3 		$384K Sell
18,690
-67,289
-78% -$1.54M ﹤0.01% 3330
2019
Q2 		$2.24M Sell
85,979
-156,665
-65% -$4.39M ﹤0.01% 2163
2019
Q1 		$9.43M Buy
242,644
+117,353
+94% +$4.76M 0.01% 1146
2018
Q4 		$5.27M Buy
125,291
+16,177
+15% +$719K 0.01% 1488
2018
Q3 		$5.46M Buy
109,114
+31,142
+40% +$1.41M 0.01% 1530
2018
Q2 		$2.98M Buy
77,972
+20,920
+37% +$901K ﹤0.01% 1924
2018
Q1 		$2.29M Buy
57,052
+50,610
+786% +$2.13M ﹤0.01% 1960
2017
Q4 		$226K Buy
+6,442
New +$188K ﹤0.01% 3377

Other funds holding WVE

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
GP
GSK plc London $599M AUM
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
MC
Maverick Capital Dallas, Texas $8.67B AUM 48.76% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Primecap Management
Primecap Management Pasadena, California $127B AUM 44.11% 1-Year Est. Return

D.E. Shaw & Co's WVE Position: Q1 2026 in Review

D.E. Shaw & Co reduced its Wave Life Sciences (WVE) stake by 73% in Q1 2026, selling an estimated $2.53M and leaving 72,305 shares worth $524K. The position accounts for ﹤0.01% of the portfolio, ranked #3831.

D.E. Shaw & Co first reported a position in WVE in Q4 2017 and has held it in 28 quarters since. The position peaked at $11.8M in Q4 2020. 230 funds tracked by Wall St. Rank hold WVE as of Q1 2026.

  • D.E. Shaw & Co held 72,305 shares of Wave Life Sciences worth $524K as of Q1 2026.
  • D.E. Shaw & Co sold 193,827 Wave Life Sciences shares in Q1 2026, an estimated $2.53M.
  • Wave Life Sciences made up ﹤0.01% of D.E. Shaw & Co's portfolio in Q1 2026, its #3831 holding.
  • D.E. Shaw & Co first reported a position in Wave Life Sciences in Q4 2017 and has held it in 28 quarters since.
  • D.E. Shaw & Co's Wave Life Sciences position peaked at $11.8M in Q4 2020.
  • 230 funds tracked by Wall St. Rank held Wave Life Sciences as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.